Raquel Eliana Lourenço Grazina Post-Doc REQUIMTE/CQFB Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa 2829-516 Caparica, Portugal Phone: + 351 212948310 ; ext-10927 Fax: + 351 212948550 e-mail: raquel.grazina@dq.fct.unl.pt
Research Interests
- Isolation and characterization of metalloproteins containing iron-sulfur centers such as ferredoxins, using specific techniques: NMR, EPR, Mössbauer and also electrochemical studies. Molecular biology research related with protein overexpression and design of single mutants. - Development of new poli-hydroxypyridinonate molecular systems with potential application in clinical and environmental uses. Synthesis, interaction with metal ions and biological studies.
Main publications
“A new immobilized hydroxypyridinone as a sequestering agent for heavy metal ions”. M. Amélia Santos, Raquel Grazina.  J. Phys. IV, 107, 1185-1188, 2003. "A new bipodal carboxy-bis(hydroxypiridinonate) ligand. Synthesis and complexation with copper(II), nickel(II) and zinc(II) in aqueous solution”.           M. Amélia Santos, Raquel Grazina, Péter Buglyó, Sofia Gama, Etelka Farkas.  Polyhedron, 21, 2609-2616, 2002. “Transition Metal Ion Complexes of Two New Amino-Dihydroxamic Acids”.      M. Amélia Santos, Raquel Grazina, Margarida Pinto, Etelka Farkas. Inorganica Chimica Acta, 321, 42-48, 2001. “Synthesis, chelating properties towards gallium and biological evaluation of two                     N-substitued 3- hydroxy-4-pyridinones”. M. A. Santos, R. Grazina, A. Q. Neto,    G. Cantinho, L.Gano, L. Patricio, J.  of Inorg. Biochem., 78,  303-311, 2000. “Siderophore Analogues. A new Macrociclic tetraminetrishydroxamate Ligand. Synthesis and Solution Chemistry of the Iron (III), Aluminium (III) and Copper (II) Complexes” . Margarida Gaspar, Raquel Grazina, Andrea Bodor, Etelka Farkas, M. Amélia Santos,   J. Chem. Soc. Dalton Trans., 799-806, 1999.