The Research Unit on Applied Molecular Biosciences, UCIBIO, is a team of researchers from the Universities of Porto and NOVA of Lisbon. The host institution is REQUIMTE, a non-profit scientific organization, between the two universities.
UCIBIO combines key expertise in Chemistry and Biological Sciences with an ambitious strategic plan to maximize its national and international impact in terms of scientific productivity, advanced training and translation to society. In the national context, UCIBIO’s key strength lies on its broad scope of fundamental and applied research standing at the interface of Chemistry and Biology to address pertinent questions at atomic, molecular, sub-cellular and cellular levels, including cell-to-cell interactions and population evolutionary dynamics.
The UCIBIO’s Strategic Scientific Plan is built around 6 general goals:
Goal 1- Generate and disseminate high quality research;
Goal 2- Pursue basic and applied research towards effective solutions of societal grand challenges;
Goal 3- Foster continuous improvement in advanced training programs and offer new ones;
Goal 4- Secure increased level of funding especially at an international level;
Goal 5- Lead the way in translation from academia to industry in Biomolecular research;
Goal 6- Develop and promote outreach activities that engage the public in our research and goals.
Our Research is centred in 4 Thematic Lines (TL) that define focus areas of research and to which the Research Groups contribute with their complementary expertise:
TL1- BIOMOLECULAR INTERACTIONS
TL2- DRUG DISCOVERY
TL3- SAFETY ASSESSMENT IN HUMAN & ENVIRONMENTAL HEALTH
TL4- MOLECULAR DIAGNOSIS & THERAPEUTICS
Research conducted at UCIBIO is highly interdisciplinary and integrative, organized around eight research groups (RG): Chem4Omics (C4O), Functional Molecules & Nanomaterials (FMN), Structural Molecular Biology (SMB), Molecular Microbiology (MM), Theoretical & Computational Biochemistry (TCB), Toxicology (TOXI), Drugs Targets & Biomarkers (DTB), Biomodels, Bioanalytics & Biophysics (BBB).
The organizational structure of UCIBIO supports its strategic plan and echoes the current research strengths and synergies within and between TLs and RGs. UCIBIO’s portfolio of competences allows addressing complex problems from different but complementary angles and using both fundamental and applied perspectives.