angelasilvanovais

Ângela Patrícia da Silva Novais Amorim
Assistant Researcher
Integrated Member
Research Group
Molecular Microbiology
Rua do Lugarinho, 15 5ºB 4250-268 Porto
966 228 110
Research Interests
The domain of specialization is the epidemiology and evolution of antibiotic-resistant bacterial populations, with special emphasis on the factors involved in the selection, dissemination and evolution of resistance genes, and especifically in the characterization of bacterial ecotypes and mobile genetic elements (plasmids, transposons and integrons). Current research interests include the characterization of the virulence profile and biofilm-producing ability of particular Escherichia coli pathotypes, and the development of scientific and technical skills in high-throughput approaches applied to the epidemiological typing, detection and characterization of particular antibiotic resistant clonal complexes.
Main publications
Rodrigues C, Machado E, Peixe L, Novais A. IncI1/ST3 and IncN/ST1 plasmids drive the spread of blaTEM-52 and blaCTX-M-1/-32 in diverse Escherichia coli clones from different piggeries. J Antimicrob Chemother. 2013 May 29. [Epub ahead of print].

Novais A, Vuotto C, Pires J, Montenegro C, Donelli G, Coque TM, Peixe L. Diversity and biofilm-production ability among isolates of Escherichia coli phylogroup D belonging to ST69, ST393 and ST405 clonal groups. BMC Microbiol. 2013. 13(1):144.

Novais A, Pires J, Ferreira H, Costa L, Montenegro C, Vuotto C, Donelli G, Coque TM, Peixe L. 2012. Characterization of globally spread Escherichia coli ST131 isolates (1991-2010). Antimicrob Agents Chemother. 2012. 56(7):3973-6.

Novais A, Comas I, González-Candelas F, Coque T, Cantón R, Moya A, Baquero F, Galán JC. (2010). Evolutionary trajectories of beta-lactamase CTX-M-1 cluster enzymes: predicting antibiotic resistance. PLoS Pathog. 6(1): e1000735. doi:10.1371/journal.ppat.1000735.

Novais A, Machado E, Canton R, Peixe L, Baquero F, Coque TM. International spread of TEM-24 is caused by the confluence of highly-penetrating Enterobacteriaceae clones and an IncA/C2 plasmid containing Tn1696::Tn1 and Tn21 flanked by IS5075. (2010) Antimicrob Agents Chemother. 54(2):825-34. IF: 4.802. Total number of times cited: 17.

Coque TM, Novais A, Carattoli A, Poirel L, Pitout J, Peixe L, Baquero F, Cantón R, Nordmann P. (2008). Dissemination of clonally related Escherichia coli strains expressing CTX-M-15 extended-spectrum ß-lactamase. Emerg Infect Dis. 14(2):195-200.