Ana Cecília Afonso Roque
Assistant Professor
Integrated Member
Research Group
Design of Molecules and NanoMaterials for Therapy and Diagnosis
Departamento de Química Faculdade de Ciências e Tecnologia Universidade Nova de Lisboa 2829-516 Caparica Portugal
212 948 385
- ext 10904
212 948 550
Research Interests
Our lab is dedicated to the molecular engineering of affinity reagents possessing biological, synthetic and hybrid scaffolds and to combine them with stimuli-responsive platforms to be applied in the Biocatalysis, Bioseparation, Biosensing and Biomedical areas. We combine molecular design techniques with synthesis, screening and selection of combinatorial libraries of ligands.
Main publications
Palma, SI, Rodrigues CA, Carvalho A, Morales PM, Freitas F, Fernandes AR, Cabral JS, Roque ACA. 2015. A value-added exopolysaccharide as a coating agent for MRI nanoprobes. Nanoscale. (7):14272-14283.

Pina, AS, Dias AMGC, Ustok FI, Khoury GE, Fernandes CSM, Branco RJF, Lowe CR, Roque ACA. 2015. Mild and cost-effective green fluorescent protein purification employing small synthetic ligands. Journal of Chromatography A. 1418:83-93.

Barroso, T, Casimiro T, Ferraria A, Mattioli F, Aguiar-Ricardo A, Roque ACA. 2014. Hybrid monoliths for magnetically-driven protein separations. Adv. Funct. Mater.. 24(28):4528–4541.

Pina, AS, Guilherme M, Pereira AS, Fernandes CSM, Branco RJF, Lowe CR, Roque ACA. 2014. A tailor made affinity pair “tag-receptor” for the purification of fusion proteins. ChemBioChem. 15(10):1423-35.