FCT NOVA
Paul Knochel

11:30 - 12:30 | Library Auditorium | Lecture by Professor Paul Knochel, University Munich, Chemistry Department, Germany

 

          Polyfunctional Heterocyclic Organometallics in Synthesis - Abstract below

 

          Host: Maria Manuel Marques, LAQV-FCT NOVA

 

 

14:00 - 17:30 | Ágora Room |  Organic Synthesis & Catalysis Workshop

 

Registration here

 

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Abstract - Polyfunctional Heterocyclic Organometallics in Synthesis

Transition metal catalyzed cross-couplings are important tools for the pharmaceutical and agrochemical industries. Herein, we will first describe the most important methods for preparing polyfunctional organozinc and organomagnesium reagents and describe their use for performing cobalt-catalyzed cross-couplings and aminations.

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[2] A. D. Benischke, M. Leroux, I. Knoll, P. Knochel Org. Lett. 2016, 18, 3626.

[3] M. S. Hofmayer, J. M. Hammann, D. Haas, P. Knochel Org. Lett. 2016, 18, 6456.
[4] J. M. Hammann, F. H. Lutter, D. Haas, P. Knochel Angew.
Chem. Int. Ed. 2017, 56, 1082.
[5] J. M. Hammann, L. Thomas, Y.-H. Chen, D. 
Haas, P. Knochel Org. Lett. 2017, 19, 3847.
[6] L. Thomas, F. H. Lutter, M. S. Hofmayer, P. Knochel Org. Lett. 2018, 20, 2441.
[7] J. Li, P. Knochel Angew. Chem. Int. Ed. 2018, 57, 11436.
[8] S. Grassl, Y.-H. Chen, C. Hamze, C.-P. Tuellmann, P. Knochel Org. Lett. 2019, 21, 494.

[9] M. S. Hofmayer, F. H. Lutter, L. Grokenberger, P. Knochel Org. Lett. 2019, 21, 36

[10] J. Li, E. Tan, N. Keller, Y.-H. Chen, T. Bein, P. Knochel J. Am. Chem. Soc. 2019, 141, 98.

[11] S. Grassl, C. Hamze, T. J. Koller, P. Knochel Chem. Eur. J. 2019, 25, 3752.

[12] Anthore-Dalion, L.; Benischke, A. D.; Knochel, P. Angew. Chem. Int. Ed. 2019, 58, 4046.

[13] Balkenhohl, M.; Zipse, H.; Karaghiosoff, K.; Knochel, P. Angew. Chem. Int. Ed. 201958, 9244.