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The Analytical Development group is composed by researchers with established background in addressing real-life problems concerning quantification of small molecules in a plethora of matrixes. They combine expertise in Instrumental Methods of Analysis, Organic Chemistry, Chemometrics, and Chemical Engineering to develop new analytical solutions using preferably sustainable methods.

The Group focuses on modernization of analytical methods, developing innovative approaches towards reduction of reagents consumption, protection of work/lab environment, deployment of point-of-care/in situ analysis, and exploitation of technological developments from other areas, namely from mechanical and electronic engineering. To achieve these goals, research efforts will aim the miniaturization of devices and methods, the advanced data analysis through chemometrics, and the development of highthroughput methods mainly through intervention on sample preparation.

Research Interests

  • Innovative sample treatment

  • Multidimensional methods for total analysis

  • Greener analytical methods

Highlights

  • Automation for monitoring dynamic systems
    On-line automated evaluation of lipid nanoparticles transdermal permeation using Franz diffusion cell and lowpressure chromatography Talanta, 2016, 146, 369-374.
    On-line automated evaluation of lipid nanoparticles transdermal permeation using Franz diffusion cell and lowpressure chromatography Talanta, 2016, 146, 369-374.

    Assessment of dynamic properties requires suitable, real-time methods because the target concentration will change along time. Automatic strategies were developed to evaluate the permeation of compounds through synthetic membranes or cell layers. In this scope, a low-pressure liquid chromatography system for the on-line quantification of caffeine loaded into lipid nanoparticles that permeates pig skin was proposed. The apparatus includes a Franz diffusion cell with computer-controlled sampling that allows collection of acceptor solution with automatic compensation for sample withdrawing, and a C-18 reversed-phase monolithic column where separation of caffeine from other matrix elements is performed before spectrophotometric quantification. Due to the real time automated sampling and high throughput, transdermal permeation profiles of nanoformulations can be established within a time frame seldom observed by conventional techniques.

     

     

     

     

     

     

  • Targeting volatiles by gas-diffusion microextraction
    Gas-diffusion microextraction coupled with spectrophotometry for the determination of formaldehyde in cork agglomerates Analytical and Bioanalytical Chemistry, 2017, 409, 2885-2892.
    Gas-diffusion microextraction coupled with spectrophotometry for the determination of formaldehyde in cork agglomerates Analytical and Bioanalytical Chemistry, 2017, 409, 2885-2892.

    Gas-diffusion microextraction (GDME) targets volatile and semi-volatile analytes present in liquid and solid samples. Its implementation is based on a dedicated device developed by LAQV researchers, where sample and acceptor fluids are separated by gas-permeable membranes. In fact, GDME is one of the few membrane-based techniques where solids are directly analyzed, without previous treatment or manipulation. The main advantage of this analytical proposal is the built-in capabilities for determination of labile fractions, surpassing reference methods. GDME is also amenable to direct coupling to different detectors (spectrophotometric, fluorimetric or electrochemical) as removal of most matrix interferences is performed in the extraction step and derivatization reagents can be added to the acceptor fluid.

     

     

     

     

     

     

     

  • Sensors for real-life applications
    SAM-based immunosensor for the analysis of thyroxine (T4) Journal of the Electrochemical Society, 2017, 164, B103-B106.
    SAM-based immunosensor for the analysis of thyroxine (T4) Journal of the Electrochemical Society, 2017, 164, B103-B106.

    Sensors based on electrochemical features are particularly tailored for real-life applications. They are adaptable to both field and lab conditions, providing almost immediate results and making them suitable for both point-of-care and screening analysis. T4, a thyroid hormone with many relevant roles in human metabolism, was determined with an antibody-based biosensor, consisting on a multi thiol self-assembled monolayer whereas anti-serpina7 polyclonal antibody was attached. Electroanalytical measurements were performed by impedance on a ferricyanide redox probe, achieving detection of target hormone above 4 ppb.

     

     

     

     

     

  • Fast, non-invasive screening methods for industrial applications
    Rapid assessment of bioactive phenolics and methylxanthines in spent coffee grounds by FT-NIR spectroscopy Talanta, 2016, 147, 460-467.
    Rapid assessment of bioactive phenolics and methylxanthines in spent coffee grounds by FT-NIR spectroscopy Talanta, 2016, 147, 460-467.

    Industry requires suitable tools for monitoring and quality control. Ideally, these tools should be noninvasive (to prevent contamination of production line, for instance) and non-destructive (to avoid economic losses from sampling for control purposes). Real-time capabilities and multi-parametric features are also sought. Infra-red spectroscopy methods offer suitable solutions for this field, as shown by several successful applications developed for pharmaceutical and food industries. A rapid and non-destructive methodology for assessing the potential of spent coffee grounds as a source of bioactive compounds was developed using near-infrared spectroscopy. High-throughput evaluation of three main phenolics (caffeic acid, (+)-catechin and chlorogenic acid) and three methylxanthines (caffeine, theobromine and theophylline) was implemented in spent coffee grounds samples obtained from different coffee brands and diverse coffee machines.

     

     

     

  • Molecular imprinting for selective analysis
    Dual-layer solid-phase extraction based on molecular imprinting technology: Seeking a route to enhance selectivity for trace analysis of pesticide residues in olive oil Electrophoresis, 2016, 37, 1916-1922.
    Dual-layer solid-phase extraction based on molecular imprinting technology: Seeking a route to enhance selectivity for trace analysis of pesticide residues in olive oil Electrophoresis, 2016, 37, 1916-1922.

    Molecular imprinting consists of preparing solid material where cavities are created by template molecules. After removal of the template, these cavities will have affinity to the template molecules or their analogues, rendering highly selective material. Their application to analytical development can follow two paths: (i) selective adsorbents for sample treatment prior to chromatographic analysis or (ii) selective recognition elements in sensors. The first approach was implemented for trace analysis of pesticide residues in olive oil, using a dual-layer cartridge packed with molecularly imprinted polymers targeting dimethoate and terbuthylazine.

     

     

     

  • Innovative sample treatment coupled to chromatography for societal challenges
    Determination of salivary cotinine through solid phase extraction using a bead-injection lab-on-valve approach hyphenated to hydrophilic interaction liquid chromatography Journal of Chromatography A, 1429, 2016, 284- 291
    Determination of salivary cotinine through solid phase extraction using a bead-injection lab-on-valve approach hyphenated to hydrophilic interaction liquid chromatography Journal of Chromatography A, 1429, 2016, 284- 291

    Current societal challenges demand access to more information regarding environmental conditions,health status, and commodities’  quality. This means a growing pressure on analysts, who have to deal with multicomponent analysis in complex samples, targeting low concentrations. In this context, sample is undeniably the bottleneck concerning analytical throughput and automation circumvents this problem. At-line automatic micro-solid phase extraction method for the determination of salivary cotinine followed by its analysis via hydrophilic interaction liquid chromatography was developed. Based on the bead injection concept incorporated in the mesofluidic lab-on-valve platform, all steps of solid-phase extraction procedure were performed without human intervention, providing a high-throughput method for evaluation of environmental tobacco exposure.

     

Representative Publications

Kohlova, M; Amorim, C; Duarte, A; Araujo, A; Solich, P; Santos-Silva, A; Montenegro, C. 2018. POLYSULFONE FLAT SHEET MEMBRANES PREPARED WITH VITAMINE E AND LIPOIC ACID TO REDUCE OXIDATIVE STRESS IN DIALYSIS. NEPHROLOGY DIALYSIS TRANSPLANTATION, 33. DOI:
Barros AA, Rodrigues JAM. Magalhães JMCS, Allegro I. 1987. Identification and Determination of Colouring Matters in CorKs Using Differential-Pulse Polarography. Portugaliae Electrochimica Acta. DOI:
Magalhães, JMCS; Machado, AASC. 1991. Uso de Eléctrodos Selectivos de Iões como Detectores em Análise por Injecção em Fluxo. Portugaliae Electrochimica Acta. DOI:
Magalhães, JMCS; Machado, AASC. 1991. Optimização de Electrodos Sanduíche para FIA. Portugaliae Electrochimica Acta. DOI:
Magalhães, JMCS; Machado, AASC. 1996. Effect of the Temperature on The Response of All-Solid-State Nonactin Ammonium ISE´s with PVC Membranes Appliled to Grphite Filled Epoxy Supports. Portugaliae Electrochimica Acta. DOI:
Magalhães, JMCS; Machado, AASC. 1997. An automatic system for determining the effects of temperature on the hysteresis curves of ion-selective electrodes. Journal of Automatic Chemistry, 19(2), 39-44. DOI:
Magalhães, JMCS; Machado, AASC. 1998. Ion Selective Electrode Array for the Determination of Benzoate in the Presence of Iodide. Portugaliae Electrochimica Acta. DOI:
Magalhaes, Jmcs; Machado, Aasc. 1993. ENZYME IMMOBILIZATION ON CHITIN AND CHITOSAN FOR CONSTRUCTION OF ENZYMATIC SENSORS. Uses of Immobilized Biological Compounds, 252, 191-200. DOI:
McsMagalhães, J; Céspedes, F; Alegret, S; AscMachado, A. 1997. Study of the temperature behaviour of all-solid-state nonactin ammonium electrodes with PVC membrane applied to graphite-epoxy supports of varied composition. ANALYTICA CHIMICA ACTA, 355(2-3), 241-247. DOI: 10.1016/S0003-2670(97)00484-4
Magalhães, JMCS; Machado, AASC. 1998. Urea potentiometric biosensor based on urease immobilized on chitosan membranes. TALANTA, 47(1), 183-191. DOI: 10.1016/S0039-9140(98)00066-6
Esteves da Silva, JCG; Dias, JRM; Magalhães, JMCS. 2001. Factorial analysis of a chemiluminescence system for bromate detection in water. ANALYTICA CHIMICA ACTA, 450(1-2), 175-184. DOI: 10.1016/S0003-2670(01)01376-9
Esteves Da Silva, JCG; Magalhães, JMCS; Fontes, R. 2001. Identification of enzyme produced firefly oxyluciferin by reverse phase HPLC. TETRAHEDRON LETTERS, 42(46), 8173-8176. DOI: 10.1016/S0040-4039(01)01754-3
Magalhães, JMCS; Machado, AASC. 2002. Array of potentiometric sensors for the analysis of creatinine in urine samples. ANALYST, 127(8), 1069-1075. DOI: 10.1039/b201173e
Correia, DPA; Magalhães, JMCS; MacHado, AASC. 2005. Array of potentiometric sensors for simultaneous analysis of urea and potassium. TALANTA, 67(4), 773-782. DOI: 10.1016/j.talanta.2005.04.003
Correia, DPA; Magalhães, JMCS; Machado, AASC. 2008. Array of potentiometric sensors for multicomponent analysis of blood serum. MICROCHIMICA ACTA, 163(1-2), 131-137. DOI: 10.1007/s00604-007-0920-y
C.Ribeiroa; C.Couto; A.R.Ribeiro; A.S.Maia; M. Santos; M.E.Tiritana; E.Pinto; A.A.Almeida. 2018. Distribution and environmental assessment of trace elements contamination of water, sediments and flora from Douro River estuary, Portugal. SCIENCE OF THE TOTAL ENVIRONMENT, 639, 1381-1393. DOI: 10.1016/j.scitotenv.2018.05.234
Couto CMCM; Ribeiro C; Maia A; Santos M; Tiritan ME; Ribeiro AR; Pinto E; Almeida A. 2018. Assessment of Douro and Ave river (Portugal) lower basin water quality focusing on physicochemical and trace element spatiotemporal changes. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING. DOI: 10.1080/10934529.2018.1474577
Manuel de Rezende Pinto; Agostinho A. Almeida. 2018. Trace Elements in the Human Milk. Trace Elements - Human Health and Environment, (). DOI: DOI: 10.5772/intechopen.76436
Ana Margarida Pereira; Edgar Pinto; Elisabete Matos; Francisco Castanheira; Agostinho A. Almeida; Cláudia S. Baptista; Marcela A. Segundo; António J. M. Fonseca; Ana R. J. Cabrita. 2018. Mineral Composition of Dry Dog Foods: Impact on Nutrition and Potential Toxicity. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 66(29), 7822-7830. DOI: 10.1021/acs.jafc.8b02552
Cabral Pinto, M.M.S.; Marinho-Reis, A.P.; Almeida, A.; Freitas, S.; Simões, M.R.; Diniz, M.L.; Pinto, E.; Ramos, P.; Ferreira da Silva, E.; Moreira, P.I.. 2018. Fingernail Trace Element Content in Environmentally Exposed Individuals and Its Influence on Their Cognitive Status in Ageing. Exposure and Health, 1-14. DOI: 10.1007/s12403-018-0274-1
Renato B.Pereira; Agostinho A.Almeida; David M.Pereira; OlgaSilva; Paula B. Andrade; Edgar Pinto; Patrícia Valentão. 2018. Trace elements in wild edible Aplysia species: Relationship with the desaturation–elongation indexes of fatty acids. CHEMOSPHERE, 208, 682-698. DOI: 10.1016/j.chemosphere.2018.06.034
Fraga, H; Faria, QT; Almeida, A; Brito, MMR; Damas, AM. 2010. Understanding calcium induced conformational changes as revealed by an 8 KDa protein from Fasciola hepatica. FEBS Journal, 277, 180-. DOI:
Costa, RCC; Almeida, AA; Araújo, AN; Silva, VL. 2002. Sequential preconcentration for the ETAAS determination of Pd in human urine. ATOMIC SPECTROSCOPY, 23(1), 17-23. DOI:
Almeida, AA; Lima, JLFC. 2001. Optimized conditions and analytical performance for the determination of Cu in serum and urine samples using a single GFAAS procedure. ATOMIC SPECTROSCOPY, 22(3), 324-330. DOI:
Almeida, AA; Lima, JLFC. 2000. Elimination of the carbon build-up effect in the ETAAS analysis of low diluted serum samples using an in situ wet digestion with tetramethylammonium hydroxide. Application to aluminium determination. JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 15(8), 1019-1024. DOI: 10.1039/b001589j
Almeida, AA; Jun, X; Lima, JLFC. 2000. Flame AAS determination of copper in urine using a flow injection on-line preconcentration system based on a polyamine chelating ion exchange column. ATOMIC SPECTROSCOPY, 21(5), 187-193. DOI:
Almeida, AA; Jun, X; Lima, JLFC. 1999. Determination of transition metals in human hair by high-performance liquid chromatography using sodium hexadecane-sulfonate coated columns. TALANTA, 50(2), 253-259. DOI: 10.1016/S0039-9140(99)00027-2
Almeida, AA; Jun, X; Lima, JLFC. 1998. High-performance liquid chromatographic determination of trace amounts of transition metals in parenteral solutions. ANALYST, 123(6), 1283-1287. DOI: 10.1039/a800553b
Almeida, AA; Cardoso, MI; Lima, JLFC. 1997. Improved determination of aluminium in port wine by electrothermal atomic absorption spectrometry using potassium dichromate chemical modification and end-capped graphite tubes. JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 12(8), 837-840. DOI:
Almeida, AA; Jun, X; Lima, JLFC. 1997. Ion Chromatographic Determination of Iodide in Urine and Serum Using a Tubular Ion-Selective Electrode Based on a Homogeneous Crystalline Membrane. Mikrochimica Acta, 127(1--2), 55-60. DOI:
Almeida, AA; Lima, JLFC. 1995. Determination of Cd, Cr, Cu, Ni, and Pb in industrial atmospheric particulate matter by ETA-AAS using solid samples directly from trapping filters. ATOMIC SPECTROSCOPY, 16(6), 261-265. DOI:
ALMEIDA, AA; CARDOSO, MI; LIMA, JLFC. 1994. DETERMINATION OF COPPER IN PORT-WINE AND MADEIRA WINE BY ELECTROTHERMAL ATOMIZATION AAS. ATOMIC SPECTROSCOPY, 15(2), 73-77. DOI:
Chiste, R; Couto, D; Freitas, M; Costa, VM; Almeida, A; Lopez Quintela, MA; Rivas, J; Freitas, P; Carvalho, F; Fernandes, E. 2015. The putative pro-inflammatory effect and oxidative stress induced by polyacrylic acid-coated iron oxide nanoparticles in mice: An biodistribution and toxicological study. TOXICOLOGY LETTERS, 238(2), S273-. DOI: 10.1016/j.toxlet.2015.08.787
Cabral Pinto, MMS; Marinho Reis, AP; Almeida, A; Ordens, CM; Silva, MMVG; Freitas, S; Simões, MR; Moreira, PI; Dinis, PA; Diniz, ML; Ferreira da Silva, EA; Condesso de Melo, MT. 2017. Human predisposition to cognitive impairment and its relation with environmental exposure to potentially toxic elements. ENVIRONMENTAL GEOCHEMISTRY AND HEALTH, 1-18. DOI: 10.1007/s10653-017-9928-3
Almeida, Agostinho A; Bastos, M. Lourdes; Cardoso, M. Isabel; Ferreira, Margarida A; Lima, José L. F. C; Soares, M. Elisa. 1992. Determination of lead and aluminium in Port Wine by electrothermal atomic absorption spectrometry. JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY. DOI: 10.1039/JA9920701281
Anabela S.G.Costa; Rita C.Alvesa; Ana F.Vinha; Elísio Costa; Catarina S.G.Costa; M. Antónia Nunes; Agostinho A.Almeida; Alice Santos-Silva; Beatriz P.P.Oliveira. 2017. Nutritional, chemical and antioxidant/pro-oxidant profiles of silverskin, a coffee roasting by-product. FOOD CHEMISTRY, 267(28), 35-. DOI: 10.1016/j.foodchem.2017.03.106
Pinto, E; Paiva, K; Carvalhido, A; Almeida, A. 2018. Elemental impurities in lipsticks: Results from a survey of the Portuguese and Brazilian markets. REGULATORY TOXICOLOGY AND PHARMACOLOGY. DOI: 10.1016/j.yrtph.2018.04.009
Galvis-Sánchez, A.C., Castro, M.C.R., Biernacki, K., Gonçalves, M.P., Souza, H.K.S.. 2018. Natural deep eutectic solvents as Green plasticizers for chitosan thermoplastic production with controlled/desired mechanical and barrier properties. Food Hydrocolloids 82(2018)478-489 DOI: 10.1016/j.foodhyd.2018.04.026. DOI:
Silva, EMP; Giuntini, F; Faustino, MAF; Tomé, JPC; Neves, MGPMS; Tomé, AC; Silva, AMS; Santana-Marques, MG; Ferrer-Correia, AJ; Cavaleiro, JAS; Caeiro, MF; Duarte, RR; Tavares, SAP; Pegado, IN; D'Almeida, B; De Matos, APA; Valdeira, ML. 2005. Synthesis of cationic β-vinyl substituted meso-tetraphenylporphyrins and their in vitro activity against herpes simplex virus type 1. Bioorganic and Medicinal Chemistry Letters, 15(14), 3333-3337. DOI: 10.1016/j.bmcl.2005.05.044
Silva, EMP; Domingues, MRM; Barros, C; Faustino, MAF; Tomé, JPC; Neves, MGPMS; Tomé, AC; Santana-Marques, MG; Cavaleiro, JAS; Ferrer-Correia, AJ. 2005. Characterization of dinitroporphyrin zinc complexes by electrospray ionization tandem mass spectrometry. Unusual fragmentations of β-(1,3-dinitroalkyl) porphyrins. JOURNAL OF MASS SPECTROMETRY, 40(1), 117-122. DOI: 10.1002/jms.789
Silva, EMP; Serra, VV; Ribeiro, AO; Tomé, JPC; Domingues, P; Faustino, MAF; Neves, MGPMS; Tomé, AC; Cavaleiro, JAS; Ferrer-Correia, AJ; Iamamoto, Y; Domingues, MRM. 2006. Characterization of cationic glycoporphyrins by electrospray tandem mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 20(23), 3605-3611. DOI: 10.1002/rcm.2766
Tomé, JPC; Silva, EMP; Pereira, AMVM; Alonso, CMA; Faustino, MAF; Neves, MGPMS; Tomé, AC; Cavaleiro, JAS; Tavares, SAP; Duarte, RR; Caeiro, MF; Valdeira, ML. 2007. Synthesis of neutral and cationic tripyridylporphyrin-d-galactose conjugates and the photoinactivation of HSV-1. Bioorganic and Medicinal Chemistry, 15(14), 4705-4713. DOI: 10.1016/j.bmc.2007.05.005
Izquierdo, RA; Barros, CM; Santana-Marques, MG; Ferrer-Correia, AJ; Silva, EMP; Giuntini, F; Faustino, MAF; Tomé, JPC; Tomé, AC; Silva, AMS; Neves, GPMS; Cavaleiro, JAS; Peixoto, AF; Pereira, MM; Pais, AACC. 2007. Characterization of Isomeric Cationic Porphyrins with β-Pyrrolic Substituents by Electrospray Mass Spectrometry: The Singular Behavior of a Potential Virus Photoinactivator. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 18(2), 218-225. DOI: 10.1016/j.jasms.2006.09.010
Silva, EMP; Domingues, P; Tomé, JPC; Faustino, MAF; Neves, MGPMS; Tomé, AC; Dauzonne, D; Silva, AMS; Cavaleiro, JAS; Ferrer-Correia, AJ; Domingues, MRM. 2008. Electrospray tandem mass spectrometry of β-nitroalkenyl meso-tetraphenylporphyrins. EUROPEAN JOURNAL OF MASS SPECTROMETRY, 14(1), 49-59. DOI: 10.1255/ejms.908
Silva, JN; Bosca, F; Tomé, JPC; Silva, EMP; Neves, MGPMS; Cavaleiro, JAS; Patterson, LK; Filipe, P; Mazière, J-C; Santus, R; Morlière, P. 2009. Tricationic porphyrin conjugates: Evidence for chain-structure-dependent relaxation of excited singlet and triplet states. JOURNAL OF PHYSICAL CHEMISTRY B, 113(52), 16695-16704. DOI: 10.1021/jp907930w
Silva, EMP; Pye, RJ; Cardin, C; Harwood, LM. 2010. Probing a biomimetic approach to mycaperoxide B: Hydroperoxidation studies. SYNLETT, 509-513. DOI: 10.1055/S-0029-1219152
Silva, JN; Galmiche, A; Tomé, JPC; Boullier, A; Neves, MGPMS; Silva, EMP; Capiod, J-C; Cavaleiro, JAS; Santus, R; Mazière, J-C; Filipe, P; Morlière, P. 2010. Chain-dependent photocytotoxicity of tricationic porphyrin conjugates and related mechanisms of cell death in proliferating human skin keratinocytes. BIOCHEMICAL PHARMACOLOGY, 80(9), 1373-1385. DOI: 10.1016/j.bcp.2010.07.033
Resende, DISP; Silva, EMP; Barros, C; Domingues, MRM; Silva, AMS; Cavaleiro, JAS. 2011. Tandem mass spectrometry based investigation of cinnamylideneacetophenone derivatives: Valuable tool for the differentiation of positional isomers. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 25(20), 3185-3195. DOI: 10.1002/rcm.5207
Silva, EMP; Silva, AMS; Cavaleiro, JAS. 2011. 1,6-Conjugated addition of nitromethane to (E)-2-styrylchromones: A new synthesis of novel 2-substituted 4-arylpyrrole derivatives. SYNLETT, 2740-2744. DOI: 10.1055/s-0031-1289525
Silva, EMP; Pye, RJ; Brown, GD; Harwood, LM. 2012. Towards the total synthesis of mycaperoxide B: Probing biosynthetic rationale. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 1209-1216. DOI: 10.1002/ejoc.201101477
Silva, EMP; Domingues, MRM; Silva, AMS; Cavaleiro, JAS. 2012. Characterisation of (E)-2-styrylchromones by electrospray ionisation mass spectrometry: Singular gas-phase formation of benzoxanthenones. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 26(19), 2251-2259. DOI: 10.1002/rcm.6345
Silva, EMP; Ramos, CIV; Pereira, PMR; Giuntini, F; Faustino, MAF; Tomé, JPC; Tomé, AC; Silva, AMS; Santana-Marques, MG; Neves, MGPMS; Cavaleiro, JAS. 2012. Cationic β-vinyl substituted meso-tetraphenylporphyrins:. JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 16(1), 101-113. DOI: 10.1142/S1088424611004373
Vaz Serra, V; Andrade, SM; Silva, EMP; Silva, AMS; Neves, MGPMS; Costa, SMB. 2013. Structural effects of the β-vinyl linker in pyridinium porphyrins: Spectroscopic studies in organic solvents and AOT reverse micelles. JOURNAL OF PHYSICAL CHEMISTRY B, 117(48), 15023-15032. DOI: 10.1021/jp4076993
Melo, T; Silva, EMP; Simões, C; Domingues, P; Domingues, MRM. 2013. Photooxidation of glycated and non-glycated phosphatidylethanolamines monitored by mass spectrometry. JOURNAL OF MASS SPECTROMETRY, 48(1), 68-78. DOI: 10.1002/jms.3129
Silva, EMP; Varandas, PAMM; Silva, AMS. 2013. Developments in the synthesis of 1,2-dihydropyridines. Synthesis (Germany), 45(22), 3053-3089. DOI: 10.1055/s-0033-1338537
Silva, EMP; Grenda, K; Cardoso, IN; Silva, AMS. 2013. 1,6-Conjugate addition of carbon nucleophiles to (E)-2-Styrylchromones: Unexpected synthesis of a stereochemically complex pentasubstituted spirocyclohexane. SYNLETT, 24(18), 2375-2382. DOI: 10.1055/s-0033-1340043
Santinha, D; Ferreira-Fernandes, E; Melo, T; Silva, EMP; Maciel, E; Fardilha, M; Domingues, P; Domingues, MRM. 2014. Evaluation of the photooxidation of galactosyl- and lactosylceramide by electrospray ionization mass spectrometry. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 28(21), 2275-2284. DOI: 10.1002/rcm.7020
Prior, J.; D. Ribeiro; J. Santos. 2013. Controlo qúımico de bebidas adulteradas em crimes facilitados com drogas. Acta Farmaĉeutica Portuguesa, 2(2), 121-134. DOI:
João L.M. Santos, S. Sofia M. Rodrigues, David S.M. Ribeiro, João A.V. Prior. 2014. Perspetivas de utilização de nanomateriais em nanodiagnóstico. Acta Farmaĉeutica Portuguesa, 3(1), 2-12. DOI:
Lima, JLFC; Prior, JAV; Reis, BF; Santos, JLM; Zagatto, EAG. 2002. Automated spectrophotometric determination of clomipramine on a multicommutated flow system. ANALYTICA CHIMICA ACTA, 467(1-2), 75-81. DOI: 10.1016/S0003-2670(02)00129-0
Prior, JAV; Santos, JLM; Lima, JLFC. 2003. Sampling strategies exploiting multi-pumping flow systems. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 375(8), 1234-1239. DOI: 10.1007/s00216-003-1813-5
Eduardo P. Borges; João A. V. Prior; Simone Vicente; João L. M. Santos; Elias A. G. Zagatto; José L. F. C. Lima. 2004. Between-method carryover in flow analysis. Journal of flow injection analysis, 21(1), 29-32. DOI:
Silva, EMP; Silva, AMS. 2012. 1,6-Conjugate Addition of Nucleophiles to α,β,γ,δ- Diunsaturated Systems. Synthesis (Germany), 44(20), 3109-3128. DOI: 10.1055/s-0032-1316778
Ricardo N.M.J. Páscoa; Silvana Moreira; João A. Lopes, Clara C. Sousa. 2018. Citrus species and hybrids depicted by near‐ and mid‐infrared spectroscopy. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE. DOI: 10.1002/jsfa.8918
Cláudia A. Teixeira dos Santos; Ricardo N.M.J. Páscoa; Patrícia A.L.S. Porto; António L. Cerdeira; J. M. González-Sáiz; C. Pizarro;João A. Lopes. 2018. Raman spectroscopy for wine analyses: A comparison with near and mid infrared spectroscopy. TALANTA, 186, 306:314-. DOI: 10.1016/j.talanta.2018.04.075
Barros, AA; Rodrigues, JA; Almeida, PJ. 1993. Determination of sulphanilic acid in the presence of tartrazine by differential-pulse polarography after conversion into an azo compound. ANALYTICA CHIMICA ACTA, 273(1-2), 539-543. DOI: 10.1016/0003-2670(93)80200-5
BARROS, AA; RODRIGUES, JAM. 1991. POLAROGRAPHIC IDENTIFICATION AND DETERMINATION OF SYNTHETIC COLORING MATTER IN CORKS. ELECTROANALYSIS, 3(3), 243-245. DOI: 10.1002/elan.1140030318
Moreira, JC; Foster, SE; Rodrigues, JA; Fogg, AG. 1992. Differential-pulse adsorptive stripping voltammetric determination of sodium cromoglycate at a hanging mercury drop electrode. ANALYST, 117(6), 989-991. DOI: 10.1039/an9921700989
Rodrigues, JA; Barros, AA. 1993. Development of a method for oxalate determination by differential-pulse polarography after derivatization with o-phenylenediamine. ANALYTICA CHIMICA ACTA, 273(1-2), 531-537. DOI: 10.1016/0003-2670(93)80199-U
Rodrigues, JA; Barros, AA. 1995. Determination of aniline by adsorptive stripping voltammetry using an improved diazotization and coupling procedure application to the evaluation of the light degradation of D&C red no. 33 in the presence of ascorbic acid. TALANTA, 42(7), 915-920. DOI:
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Barros, A; Rodrigues, JA; Almeida, PJ; Oliva-Teles, MT. 1999. Determination of glyoxal, methylglyoxal, and diacetyl in selected beer and wine, by HPLC with UV spectrophotometric detection, after derivatization with o-phenylenediamine. Journal of Liquid Chromatography and Related Technologies, 22(13), 2061-2069. DOI: 10.1081/JLC-100101786
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Guido, LF; Fortunato, NA; Rodrigues, JA; Barros, AA. 2003. Voltammetric assay for the aging of beer. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 51(14), 3911-3915. DOI: 10.1021/jf020895u
Guido, LF; Rodrigues, PG; Rodrigues, JA; Gonçalves, CR; Barros, AA. 2004. The impact of the physiological condition of the pitching yeast on beer flavour stability: An industrial approach. FOOD CHEMISTRY, 87(2), 187-193. DOI: 10.1016/j.foodchem.2003.10.033
Carneiro, JR; Guido, LF; Almeida, PJ; Rodrigues, JA; Barros, AA. 2006. The impact of sulphur dioxide and oxygen on the behaviour of 2-furaldehyde in beer: an industrial approach. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 41(5), 545-552. DOI: 10.1111/j.1365-2621.2005.01104.x
Carneiro, JR; Ferreira, JA; Guido, LF; Almeida, PJ; Rodrigues, JA; Barros, AA. 2006. Determination of β-damascenone in alcoholic beverages by reversed-phase liquid chromatography with ultraviolet detection. FOOD CHEMISTRY, 99(1), 51-56. DOI: 10.1016/j.foodchem.2005.07.024
Rodrigues, J; Almeida, P. 2008. E-2-nonenal and β-damascenone in beer. Beer in Health and Disease Prevention, 395-402. DOI:
Xiong, L; Batchelor-McAuley, C; Gonçalves, LM; Rodrigues, JA; Compton, RG. 2011. The indirect electrochemical detection and quantification of DNA through its co-adsorption with anthraquinone monosulphonate on graphitic and multi-walled carbon nanotube screen printed electrodes. Biosensors and Bioelectronics, 26(10), 4198-4203. DOI: 10.1016/j.bios.2011.04.039
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Pasion, R; Fernandes, C; Gonçalves, AR; Ferreira-Santos, F; Páscoa, R; Barbosa, F; Marques-Teixeira, J. 2018. The effect of aging on the (mis)perception of intentionality - an ERP study. Social Neuroscience, 1-13. DOI: 10.1080/17470919.2018.1430614
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Páscoa, RNMJ; Tóth, IV; Rangel, AOSS. 2009. Sequential injection trace determination of iron in natural waters using a long-pathlength liquid core waveguide and different spectrophotometric chemistries. LIMNOLOGY AND OCEANOGRAPHY-METHODS, 7(NOV), 795-802. DOI:
Dias, AMA; Moita, I; Páscoa, R; Alves, MM; Lopes, JA; Ferreira, EC. 2008. Activated sludge process monitoring through in situ near-infrared spectral analysis. WATER SCIENCE AND TECHNOLOGY, 57(10), 1643-1650. DOI: 10.2166/wst.2008.147
Páscoa, RNMJ; Vidigal, SSMP; Tóth, IV; Rangel, AOSS. 2006. Sequential injection system for the enzymatic determination of ethanol in wine. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 54(1), 19-23. DOI: 10.1021/jf051787l
Pedro Francisco Brandão; Rui Miguel Ramos; José António Rodrigues. 2018. GDME-based methodology for the determination of free formaldehyde in cosmetics and hygiene products containing formaldehyde releasers. ANALYTICAL AND BIOANALYTICAL CHEMISTRY. DOI: 10.1007/s00216-018-1287-0
P. J. Almeida, J. A. Rodrigues, L. F. Guido, J. R. Santos, A. A. Barros and A. G. Fogg. 2003. Free Sulfur Dioxide in Beer as the Difference Between Total Sulfur Dioxide and Acetaldehyde: A Voltammetric Approach. ASBC, 61, 191-. DOI: 10.1094/asbcj-61-0191
Manuela BTSousa; João Rodrigo Santos; PJAlmeida; JARodrigues. 2018. Low pressure ion pair chromatography with amperometric detection for the determination of trigonelline in coffee samples. FOOD RESEARCH INTERNATIONAL, 114, 223-. DOI: 10.1016/j.foodres.2018.07.068
Silva Filho, Silverio Ferreira; Pereira, Andreia Cardoso; Sarraguca, Jorge MG; Sarraguca, Mafalda C; Lopes, Joao; Facanha Filho, Pedro de Freitas; dos Santos, Adenilson Oliveira; da Silva Ribeiro, Paulo Roberto. 2018. Synthesis of a Glibenclamide Cocrystal: Full Spectroscopic and Thermal Characterization. JOURNAL OF PHARMACEUTICAL SCIENCES, 107(6), 1597-1604. DOI: 10.1016/j.xphs.2018.01.029
Silva, AF; Vercruysse, J; Vervaet, C; Remon, JP; Lopes, JA; De Beer, T; Sarraguca, MC. 2018. Process monitoring and evaluation of a continuous pharmaceutical twin-screw granulation and drying process using multivariate data analysis. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 128, 36-47. DOI: 10.1016/j.ejpb.2018.04.011
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Leitǎo, MLP; Canotilho, J; Cruz, MSC; Pereira, JC; Sousa, AT; Redinha, JS. 2002. Study of polymorphism from DSC melting curves. Polymorphs of terfenadine. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 68(2), 397-412. DOI: 10.1023/A:1016023315613
Eusébio, ME; Lopes Jesus, AJ; Cruz, MSC; Leitão, MLP; Redinha, JS. 2003. Enthalpy of vaporisation of butanediol isomers. JOURNAL OF CHEMICAL THERMODYNAMICS, 35(1), 123-129. DOI: 10.1016/S0021-9614(02)00306-3
Canotilho, J; Castro, RAE; Rosado, MTS; Nunes, SCC; Cruz, MSC; Redinha, JS. 2010. Thermal analysis and crystallization from melts: β-adrenergic compounds. JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY, 100(2), 423-429. DOI: 10.1007/s10973-009-0645-8
Mafalda CSarraguca; Ricardo Pascoa; Miguel Lopo; Jorge Sarraguca; Joao ALopes. 2016. Bioactive Compounds in Coffee as Health Promotors. Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters Part II, 180-. DOI: 10.2174/9781681082431116010011
Martins, JG; Martin, C; Hernandez-Apaolaza, L; Barros, MT; Soares, HMVM; Lucena, JJ. 2018. Azotochelin and N-dihydroxy-N, N '-diisopropylhexanediamide as Fe sources to cucumber plants in hydroponic cultures. Emirates Journal of Food and Agriculture, 30, 65-76. DOI: 10.9755/ejfa.2018.v30.i1.1586
Couto, RAS; Goncalves, LM; Carvalho, F; Rodrigues, JA; Rodrigues, CMP; Quinaz, MB. 2018. The Analytical Challenge in the Determination of Cathinones, Key-Players in the Worldwide Phenomenon of Novel Psychoactive Substances. CRITICAL REVIEWS IN ANALYTICAL CHEMISTRY, 48, 372-390. DOI: 10.1080/10408347.2018.1439724
Cardoso, O; Donato, MM; Luxo, C; Almeida, N; Liberal, J; Figueirinha, A; Batista, MT. 2018. Anti-Helicobacter pylori potential of Agrimonia eupatoria L. and Fragaria vesca. Journal of Functional Foods, 44, 299-303. DOI: 10.1016/j.jff.2018.03.027
Cordeiro, L; Valente, IM; Santos, JR; Rodrigues, JA. 2018. Qualitative carbonyl profile in coffee beans through GDME-HPLC-DAD-MS/MS for coffee preliminary characterization. FOOD RESEARCH INTERNATIONAL, 107, 536-543. DOI: 10.1016/j.foodres.2018.02.072
Custodio-Mendoza, JA; Lorenzo, RA; Valente, IM; Almeida, PJ; Gage, MA; Rodrigues, JA; Carro, AM. 2018. Development of a partitioned liquid-liquid extraction- dispersive solid phase extraction procedure followed by liquid chromatography-tandem mass spectrometry for analysis of 3-monochloropropane-1,2-diol diesters in edible oils. JOURNAL OF CHROMATOGRAPHY A, 1548, 19-26. DOI: 10.1016/j.chroma.2018.03.017
Lopo, M; dos Santos, CAT; Pascoa, RNMJ; Graca, AR; Lopes, JA. 2018. Near infrared spectroscopy as a tool for intensive mapping of vineyards soil. PRECISION AGRICULTURE, 19, 445-462. DOI: 10.1007/s11119-017-9529-2
Nouws, HPA; Delerue-Matos, C; Barros, AA; Rodrigues, JA. 2005. Electroanalytical study of the antidepressant sertraline. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 39, 290-293. DOI: 10.1016/j.jpba.2005.02.040
Lopes, CMPV; Almeida, AA; Santos, JLM; Lima, JLFC. 2006. Automated multicommutated flow system for flame atomic spectroscopy determination of rubidium at high concentrations. ATOMIC SPECTROSCOPY, 27, 13-18. DOI:
Lopes, CMPV; Almeida, AA; Santos, JLM; Lima, JLFC. 2006. Automatic flow system for the sequential determination of copper in serum and urine by flame atomic absorption spectrometry. ANALYTICA CHIMICA ACTA, 555, 370-376. DOI: 10.1016/j.aca.2005.09.013
Lopes, CMPV; Almeida, AA; Santos, JLM; Lima, JLFC. 2006. Coupling of multi-pumping flow systems to flame atomic spectrometric detectors: Preliminary studies and analytical applications in the analysis of biological samples. ATOMIC SPECTROSCOPY, 27, 156-164. DOI:
Nouws, HPA; Delerue-Matos, C; Barros, AA; Rodrigues, JA. 2006. Electroanalytical determination of paroxetine in pharmaceuticals. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 42, 341-346. DOI: 10.1016/j.jpba.2006.04.015
Santos, A; Magalhaes, T; Vieira, DN; Almeida, AA; Sousa, AV. 2007. Firing distance estimation through the analysis of the gunshot residue deposit pattern around the bullet entrance hole by inductively coupled plasma-mass spectrometry - An experimental study. AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY, 28, 24-30. DOI: 10.1097/01.paf.0000233631.40170.d4
Lopes, CMPV; Almeida, AA; Saraiva, MLMFS; Lima, JLFC. 2007. Determination of Rh, Pd and Pt in urine samples using a pre-concentration sequential injection analysis system coupled to a quadrupole-inductively coupled plasma-mass spectrometer. ANALYTICA CHIMICA ACTA, 600, 226-232. DOI: 10.1016/j.aca.2007.02.068
Almeida, AA; Lopes, CMPV; Silva, AMS; Barrado, E. 2008. Trace elements in human milk: Correlation with blood levels, inter-element correlations and changes in concentration during the first month of lactation. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 22, 196-205. DOI: 10.1016/j.jtemb.2008.03.007
Pascoa, RNM; Lopes, JA; Lima, JLFC. 2008. In situ near infrared monitoring of activated dairy sludge wastewater treatment processes. JOURNAL OF NEAR INFRARED SPECTROSCOPY, 16, 409-419. DOI: 10.1255/jnirs.803
Fonseca, C; Neves, AR; Antunes, AMM; Noronha, JP; Hahn-Hagerdal, B; Santos, H; Spencer-Martins, I. 2008. Use of in vivo C-13 nuclear magnetic resonance Spectroscopy to elucidate L-arabinose metabolism in Yeasts. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 74, 1845-1855. DOI: 10.1128/AEM.02453-07
Sarraguca, MC; Lopes, JA. 2009. Quality control of pharmaceuticals with NIR: From lab to process line. VIBRATIONAL SPECTROSCOPY, 49, 204-210. DOI: 10.1016/j.vibspec.2008.07.013
Sarraguca, MC; Lopes, JA. 2009. The use of net analyte signal (NAS) in near infrared spectroscopy pharmaceutical applications: Interpretability and figures of merit. ANALYTICA CHIMICA ACTA, 642, 179-185. DOI: 10.1016/j.aca.2008.10.006
Sarraguca, MC; Paulo, A; Alves, MM; Dias, AMA; Lopes, JA; Ferreira, EC. 2009. Quantitative monitoring of an activated sludge reactor using on-line UV-visible and near-infrared spectroscopy. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 395, 1159-1166. DOI: 10.1007/s00216-009-3042-z
Goncalves, LM; Pacheco, JG; Magalhaes, PJ; Rodrigues, JA; Barros, AA. 2010. Determination of free and total sulfites in wine using an automatic flow injection analysis system with voltammetric detection. Food Additives and Contaminants Part A-Chemistry Analysis Control Exposure & Risk Assessment, 27, 175-180. DOI: 10.1080/19440040903261547
Carvalhido, JAE; Almeida, AA; Araujo, AN; Montenegro, MCBSM. 2010. A Reflectance Flow-through Thionine Sol-gel Sensor for the Determination of Se(IV). ANALYTICAL SCIENCES, 26, 665-669. DOI: 10.2116/analsci.26.665
Sarraguca, MC; De Beer, T; Vervaet, C; Remon, JP; Lopes, JA. 2010. A batch modelling approach to monitor a freeze-drying process using in-line Raman spectroscopy. TALANTA, 83, 130-138. DOI: 10.1016/j.talanta.2010.08.051
Fraga, H; Faria, TQ; Pinto, F; Almeida, A; Brito, RMM; Damas, AM. 2010. FH8-a small EF-hand protein from Fasciola hepatica. FEBS Journal, 277, 5072-5085. DOI: 10.1111/j.1742-4658.2010.07912.x
Alves, GMS; Magalhaes, JMCS; Soares, HMVM. 2011. Simultaneous Determination of Copper(II), Lead(II) and Zinc(II) at Bismuth Film Electrode by Multivariate Calibration. ELECTROANALYSIS, 23, 1410-1417. DOI: 10.1002/elan.201000696
Pascoa, RNMJ; Toth, IV; Rangel, AOSS. 2011. Spectrophotometric determination of zinc and copper in a multi-syringe flow injection analysis system using a liquid waveguide capillary cell: Application to natural waters. TALANTA, 84, 1267-1272. DOI: 10.1016/j.talanta.2011.01.023
Almeida, MIGS; Estela, JM; Segundo, MA; Cerda, V. 2011. A membraneless gas-diffusion unit - multisyringe flow injection spectrophotometric method for ammonium determination in untreated environmental samples. TALANTA, 84, 1244-1252. DOI: 10.1016/j.talanta.2010.12.052
Sarraguca, MC; Soares, SO; Lopes, JA. 2011. A near-infrared spectroscopy method to determine aminoglycosides in pharmaceutical formulations. VIBRATIONAL SPECTROSCOPY, 56, 184-192. DOI: 10.1016/j.vibspec.2011.02.007
Rodrigues, PG; Goncalves, LM; Magalhaes, PJ; Pacheco, JG; Rodrigues, JA; Barros, AA. 2011. Voltammetric analysis of metallothioneins and copper (II) in fish for water biomonitoring studies. Environmental Chemistry Letters, 9, 405-410. DOI: 10.1007/s10311-010-0293-z
Pascoa, RNMJ; Toth, IV; Almeida, AA; Rangel, AOSS. 2011. Spectrophotometric sensor system based on a liquid waveguide capillary cell for the determination of titanium: Application to natural waters, sunscreens and a lake sediment. SENSORS AND ACTUATORS B-CHEMICAL, 157, 51-56. DOI: 10.1016/j.snb.2011.03.025
Alves, GMS; Magalhaes, JMCS; Salaun, P; van den Berg, CMG; Soares, HMVM. 2011. Simultaneous electrochemical determination of arsenic, copper, lead and mercury in unpolluted fresh waters using a vibrating gold microwire electrode. ANALYTICA CHIMICA ACTA, 703, 1-7. DOI: 10.1016/j.aca.2011.07.022
Cerca, F; Andrade, F; Franca, A; Andrade, EB; Ribeiro, A; Almeida, AA; Cerca, N; Pier, G; Azeredo, J; Vilanova, M. 2011. Staphylococcus epidermidis biofilms with higher proportions of dormant bacteria induce a lower activation of murine macrophages. JOURNAL OF MEDICAL MICROBIOLOGY, 60, 1717-1724. DOI: 10.1099/jmm.0.031922-0
Lourenco, D; Sarraguca, M; Alves, G; Coutinho, P; Araujo, ARTS; Rodrigues, M. 2017. A novel HPLC method for the determination of zonisamide in human plasma using microextraction by packed sorbent optimised by experimental design. Analytical Methods, 9, 5910-5919. DOI: 10.1039/c7ay01912b
dos Santos, CAT; Pascoa, RNMJ; Sarraguca, MC; Porto, PALS; Cerdeira, AL; Gonzalez-Saiz, JM; Pizarro, C; Lopes, JA. 2017. Merging vibrational spectroscopic data for wine classification according to the geographic origin. FOOD RESEARCH INTERNATIONAL, 102, 504-510. DOI: 10.1016/j.foodres.2017.09.018
Tahri, K; Duarte, AA; Carvalho, G; Ribeiro, PA; da Silva, MG; Mendes, D; El Bari, N; Raposo, M; Bouchikhi, B. 2018. Distinguishment, identification and aroma compound quantification of Portuguese olive oils based on physicochemical attributes, HS-GC/MS analysis and voltammetric electronic tongue. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 98, 681-690. DOI: 10.1002/jsfa.8515
Machado, JC; Faria, MA; Ferreira, IMPLVO; Pascoa, RNMJ; Lopes, JA. 2018. Varietal discrimination of hop pellets by near and mid infrared spectroscopy. TALANTA, 180, 69-75. DOI: 10.1016/j.talanta.2017.12.030
Aires-de-Sousa, J; Cardoso, MM; Ferreira, LM; Lima, JC; Noronha, JP; Nunes, AVM; da Ponte, MN. 2017. Team-Based Learning in Chemistry Courses with Laboratory Sessions. BIODEVICES: PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON BIOMEDICAL ELECTRONICS AND DEVICES, 1213-1218. DOI: 10.4995/HEAd17.2017.5559
ben Hammouda, I; Freitas, Fxxxxxxxxxx; Ammar, S; Da Silva, MDRG; Bouaziz, M. 2017. Comparison and characterization of volatile compounds as markers of oils stability during frying by HS-SPME-GC/MS and Chemometric analysis. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 1068, 322-334. DOI: 10.1016/j.jchromb.2017.10.063
Sarraguça, MC; Cruz, AV; Amaral, HR; Costa, PC; Lopes, JA. 2011. Comparison of different chemometric and analytical methods for the prediction of particle size distribution in pharmaceutical powders. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 399(6), 2137-2147. DOI: 10.1007/s00216-010-4230-6
Sarraguça, MC; Cruz, AV; Soares, SO; Amaral, HR; Costa, PC; Lopes, JA. 2010. Determination of flow properties of pharmaceutical powders by near infrared spectroscopy. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 52(4), 484-492. DOI: 10.1016/j.jpba.2010.01.038
Santos, JR; Carneiro, JR; Guido, LF; Almeida, PJ; Rodrigues, JA; Barros, AA. 2003. Determination of E-2-nonenal by high-performance liquid chromatography with UV detection: Assay for the evaluation of beer ageing. JOURNAL OF CHROMATOGRAPHY A, 985(1-2), 395-402. DOI: 10.1016/S0021-9673(02)01396-1
Guido, LF; Carneiro, JR; Santos, JR; Almeida, PJ; Rodrigues, JA; Barros, AA. 2004. Simultaneous determination of E-2-nonenal and β-damascenone in beer by reversed-phase liquid chromatography with UV detection. JOURNAL OF CHROMATOGRAPHY A, 1032(1-2), 17-22. DOI: 10.1016/j.chroma.2003.12.026
Páscoa, RNMJ; Sarraguça, MC; Magalhães, LM; Santos, JR; Rangel, AOSS; Lopes, JA. 2014. Use of Near-Infrared Spectroscopy for Coffee Beans Quality Assessment. Coffee in Health and Disease Prevention, 933-942. DOI: 10.1016/B978-0-12-409517-5.00103-0
Tiago ACatelani; João Rodrigo Santos; Ricardo NMJPáscoa; Leonardo Pezza; Helena RPezza; João ALopes. 2017. Real-time monitoring of a coffee roasting process with near infrared spectroscopy using multivariate statistical analysis: a feasibility study. TALANTA. DOI: 10.1016/j.talanta.2017.11.010
Almeida, PJ; Rodrigues, JA; Guido, LF; Santos, JR; Barros, AA; Fogg, AG. 2003. Voltammetric determination of free and total sulfur dioxide in beer. ELECTROANALYSIS, 15(5-6), 587-590. DOI:
Nouws, HPA; Delerue Matos, C; Barros, AA; Rodrigues, JA; Santos Silva, A; Borges, F. 2007. Square-wave adsorptive-stripping voltammetric detection in the quality control of fluoxetine. ANALYTICAL LETTERS. DOI: 10.1080/00032710701297059
Pacheco, JG; Valente, IM; Gonçalves, LM; Magalhães, PJ; Rodrigues, JA; Barros, AA. 2010. Development of a membraneless extraction module for the extraction of volatile compounds: Application in the chromatographic analysis of vicinal diketones in beer. TALANTA, 81(1-2), 372-376. DOI: 10.1016/j.talanta.2009.12.011
Gonçalves, LM; Da Anunciação, MF; Valente, IM; Pacheco, JG; Rodrigues, JA; Barros, AA. 2010. Use of a membraneless extraction module for the voltammetric determination of total sulfites in wine. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 75(7), 721-730. DOI: 10.1135/cccc2009558
Rodrigues, JA; Valente, IM; Gonçalves, LM; Pacheco, JG; Barros, AA. 2010. Polarographic determination of vitamin C after derivatization with o-phenylenediamine. COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 75(7), 731-741. DOI: 10.1135/cccc2010026
Gonçalves, LM; Magalhães, PJ; Valente, IM; Pacheco, JG; Dostálek, P; Sýkora, D; Rodrigues, JA; Barros, AA. 2010. Analysis of aldehydes in beer by gas-diffusion microextraction: Characterization by high-performance liquid chromatography-diode-array detection-atmospheric pressure chemical ionization-mass spectrometry. JOURNAL OF CHROMATOGRAPHY A, 1217(24), 3717-3722. DOI: 10.1016/j.chroma.2010.04.002
Pacheco, JG; Valente, IM; Gonçalves, LM; Rodrigues, JA; Barros, AA. 2010. Gas-diffusion microextraction. JOURNAL OF SEPARATION SCIENCE, 33(20), 3207-3212. DOI: 10.1002/jssc.201000351
Montenegro, P; Valente, IM; Gonalves, LM; Rodrigues, JA; Barros, AA. 2011. Single determination of α-ketoglutaric acid and pyruvic acid in beer by HPLC with UV detection. Analytical Methods, 3(5), 1207-1212. DOI: 10.1039/c0ay00669f
Moreira, MM; Carvalho, AM; Valente, IM; Gonçalves, LM; Rodrigues, JA; Barros, AA; Guido, LF. 2011. Novel application of square-wave adsorptive-stripping voltammetry for the determination of xanthohumol in spent hops. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 59(14), 7654-7658. DOI: 10.1021/jf2011485
Ramos, RM; Pacheco, JG; Gonçalves, LM; Valente, IM; Rodrigues, JA; Barros, AA. 2012. Determination of free and total diacetyl in wine by HPLC-UV using gas-diffusion microextraction and pre-column derivatization. FOOD CONTROL, 24(1-2), 220-224. DOI: 10.1016/j.foodcont.2011.07.017
Gonçalves, LM; Moreira, MM; Azevedo, CF; Valente, IM; Sousa, JC; Scanlan, TS; Compton, RG; Rodrigues, JA. 2014. Proof of Concept of the Electrochemical Sensing of 3-Iodothyronamine (T<inf>1</inf>AM) and Thyronamine (T<inf>0</inf>AM). ChemElectroChem, 1(10), 1623-1626. DOI: 10.1002/celc.201402165
Harasimowicz, J; Marques, KL; Silva, AFT; Costa, RCB; Prior, JAV; Rodrigues, SSM; Santos, JLM. 2012. Chemiluminometric evaluation of melatonin and selected melatonin precursors' interaction with reactive oxygen and nitrogen species. ANALYTICAL BIOCHEMISTRY, 420, 1-6. DOI: 10.1016/j.ab.2011.09.008
Laureys, T; Pinto, ISS; Soares, CVM; Boppudi, HB; Soares, HMVM. 2012. Complexation of 1,3-Bis(tris(hydroxymethyl)methylamino)propane Systems Involving Divalent (Cobalt, Nickel, or Zinc) Ions in Aqueous Solution by Potentiometry. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 57, 87-92. DOI: 10.1021/je200809m
Sarraguca, JMG; Lopes, JA; Santos, JLM; Lima, JLFC. 2012. MATHEMATICAL SIMULATION OF SIGNAL PROFILES IN FLOW ANALYSIS. ANALYTICAL LETTERS, 45, 85-98. DOI: 10.1080/00032719.2011.582551
Morliere, P; Patterson, LK; Santos, CMM; Silva, AMS; Maziere, JC; Filipe, P; Gomes, A; Fernandes, E; Garcia, MBQ; Santus, R. 2012. The dependence of alpha-tocopheroxyl radical reduction by hydroxy-2,3-diarylxanthones on structure and micro-environment. ORGANIC & BIOMOLECULAR CHEMISTRY, 10, 2068-2076. DOI: 10.1039/c2ob06612b
Almeida, SAA; Heitor, AM; Sa, LC; Barbosa, J; da Conceicao, M; Montenegro, BSM; Sales, MGF. 2012. Solid contact PVC membrane electrodes based on neutral or charged carriers for the selective reading of anionic sulfamethoxazole and their application to the analysis of aquaculture water. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 92, 479-495. DOI: 10.1080/03067319.2011.585717
Lopes, SB; Sarraguca, JM; Prior, JAV; Lopes, JA. 2012. DEVELOPMENT OF AN HPLC ASSAY METHODOLOGY FOR A DESONIDE CREAM WITH CHEMOMETRICS ASSISTED OPTIMIZATION. ANALYTICAL LETTERS, 45, 1390-1400. DOI: 10.1080/00032719.2012.675494
Valente, IM; Santos, CM; Goncalves, LM; Rodrigues, JA; Barros, AA. 2012. Application of gas-diffusion microextraction for high-performance liquid chromatographic analysis of aliphatic amines in fermented beverages. Analytical Methods, 4, 2569-2573. DOI: 10.1039/c2ay25272d
Moreira, FTC; Dutra, RAF; Noronha, JPC; Sales, MGF. 2012. Surface Imprinting approach on screen printed electrodes coated with carboxylated PVC for Myoglobin detection with Electrochemical Transduction. ENGINEERING OF SPORT 10, 47, 865-868. DOI: 10.1016/j.proeng.2012.09.284
Queiros, RB; Noronha, JP; Marques, PVS; Sales, MGF. 2012. Label-free Detection of Microcystin-LR in Waters Using Real-Time Potentiometric Biosensors Based on Single-Walled Carbon Nanotubes Imprinted Polymers. ENGINEERING OF SPORT 10, 47, 758-761. DOI: 10.1016/j.proeng.2012.09.258
Neves, AR; Lucio, M; Lima, JLC; Reis, S. 2012. Resveratrol in Medicinal Chemistry: A Critical Review of its Pharmacokinetics, Drug-Delivery, and Membrane Interactions. CURRENT MEDICINAL CHEMISTRY, 19, 1663-1681. DOI:
Soares, EV; Soares, HMVM. 2012. Bioremediation of industrial effluents containing heavy metals using brewing cells of Saccharomyces cerevisiae as a green technology: a review. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 19, 1066-1083. DOI: 10.1007/s11356-011-0671-5
Oliveira, SM; Oliveira, HM; Segundo, MA; Rangel, AOSS; Lima, JLFC; Cerda, V. 2012. Automated solid-phase spectrophotometric system for optosensing of bromate in drinking waters. Analytical Methods, 4, 1229-1236. DOI: 10.1039/c2ay05860j
Cruz, MP; Valente, IM; Goncalves, LM; Rodrigues, JA; Barros, AA. 2012. Application of gas-diffusion microextraction to the analysis of free and bound acetaldehyde in wines by HPLC-UV and characterization of the extracted compounds by MS/MS detection. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 403, 1031-1037. DOI: 10.1007/s00216-011-5664-1
Moreira, MM; Morais, S; Barros, AA; Delerue-Matos, C; Guido, LF. 2012. A novel application of microwave-assisted extraction of polyphenols from brewer's spent grain with HPLC-DAD-MS analysis. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 403, 1019-1029. DOI: 10.1007/s00216-011-5703-y
Almeida, SAA; Truta, LAANA; Queiros, RB; Montenegro, MCBSM; Cunha, AL; Sales, MGF. 2012. Optimizing potentiometric ionophore and electrode design for environmental on-site control of antibiotic drugs: Application to sulfamethoxazole. BIOSENSORS & BIOELECTRONICS, 35, 319-326. DOI: 10.1016/j.bios.2012.03.007
Sousa, CT; Nunes, C; Proenca, MP; Leitao, DC; Lima, JLFC; Reis, S; Araujo, JP; Lucio, M. 2012. pH sensitive silica nanotubes as rationally designed vehicles for NSAIDs delivery. COLLOIDS AND SURFACES B-BIOINTERFACES, 94, 288-295. DOI: 10.1016/j.colsurfb.2012.02.003
Magalhaes, LM; Almeida, MIGS; Barreiros, L; Reis, S; Segundo, MA. 2012. Automatic Aluminum Chloride Method for Routine Estimation of Total Flavonoids in Red Wines and Teas. Food Analytical Methods, 5, 530-539. DOI: 10.1007/s12161-011-9278-1
Pinto, PCAG; Costa, SPF; Lima, JLFC; Saraiva, MLMFS. 2012. Automated high-throughput Vibrio fischeri assay for (eco)toxicity screening: Application to ionic liquids. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 80, 97-102. DOI: 10.1016/j.ecoenv.2012.02.013
Vaz, AM; Araujo, ARTS; Santos, JLM; Lima, JLFC; Saraiva, MLMFS. 2012. Automatic miniaturized flow methodology with in-line solid-phase extraction for quinine determination in biological samples. Analytical Methods, 4, 1681-1686. DOI: 10.1039/c2ay05818a
Carvalho, AM; Goncalves, LM; Valente, IM; Rodrigues, JA; Barros, AA. 2012. Analysis of Cardamonin by Square Wave Voltammetry. PHYTOCHEMICAL ANALYSIS, 23, 396-399. DOI: 10.1002/pca.1370
Novais, A; Pires, J; Ferreira, H; Costa, L; Montenegro, C; Vuotto, C; Donelli, G; Coque, TM; Peixe, L. 2012. Characterization of Globally Spread Escherichia coli ST131 Isolates (1991 to 2010). ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 56, 3973-3976. DOI: 10.1128/AAC.00475-12
Pinto, PCAG; Costa, SPF; Costa, ADF; Passos, ML; Lima, JLFC; Saraiva, MLMFS. 2012. Trypsin activity in imidazolium based ionic liquids: evaluation of free and immobilized enzyme. JOURNAL OF MOLECULAR LIQUIDS, 171, 16-22. DOI: 10.1016/j.molliq.2012.04.004
Pinto, PCAG; Costa, SPF; Lima, JLFC; Saraiva, MLMFS. 2012. beta-Galactosidase activity in mixed micelles of imidazolium ionic liquids and sodium dodecylsulfate: A sequential injection kinetic study. TALANTA, 96, 26-33. DOI: 10.1016/j.talanta.2012.02.020
Ribeiro, DSM; Frigerio, C; Santos, JLM; Prior, JAV. 2012. Photoactivation by visible light of CdTe quantum dots for inline generation of reactive oxygen species in an automated multipumping flow system. ANALYTICA CHIMICA ACTA, 735, 69-75. DOI: 10.1016/j.aca.2012.05.034
Frigerio, C; Ribeiro, DSM; Rodrigues, SSM; Abreu, VLRG; Barbosa, JAC; Prior, JAV; Marques, KL; Santos, JLM. 2012. Application of quantum dots as analytical tools in automated chemical analysis: A review. ANALYTICA CHIMICA ACTA, 735, 9-22. DOI: 10.1016/j.aca.2012.04.042
Abreu, VLRG; Santos, JLM; Lima, JLFC. 2012. An Automated Single Interface Flow System for the Spectrophotometric Determination of Ethanol in Beverages Based on Schlieren Effect. Food Analytical Methods, 5, 867-873. DOI: 10.1007/s12161-011-9322-1
Placido, A; Kupers, R; Paiga, P; Magalhaes, J; Nouws, HPA; Delerue-Matos, C; Oliveira, MBPP. 2012. Salt content in bread and dough from northern Portugal: Method development and comparison. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 27, 14-20. DOI: 10.1016/j.jfca.2012.04.004
Ferraz, P; Fidalgo, F; Almeida, A; Teixeira, J. 2012. Phytostabilization of nickel by the zinc and cadmium hyperaccumulator Solanum nigrum L. Are metallothioneins involved?. PLANT PHYSIOLOGY AND BIOCHEMISTRY, 57, 254-260. DOI: 10.1016/j.plaphy.2012.05.025
Magalhaes, LM; Barreiros, L; Maia, MA; Reis, S; Segundo, MA. 2012. Rapid assessment of endpoint antioxidant capacity of red wines through microchemical methods using a kinetic matching approach. TALANTA, 97, 473-483. DOI: 10.1016/j.talanta.2012.05.002
Pascoa, RNMJ; Toth, IV; Rangel, AOSS. 2012. Review on recent applications of the liquid waveguide capillary cell in flow based analysis techniques to enhance the sensitivity of spectroscopic detection methods. ANALYTICA CHIMICA ACTA, 739, 1-13. DOI: 10.1016/j.aca.2012.05.058
Lourenco, ND; Lopes, JA; Almeida, CF; Sarraguca, MC; Pinheiro, HM. 2012. Bioreactor monitoring with spectroscopy and chemometrics: a review. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 404, 1211-1237. DOI: 10.1007/s00216-012-6073-9
Castro, CM; Pinheiro, M; Casares, JJ; Lucio, M; Segundo, M; Reis, S; Lima, JLFC. 2012. Study of antioxidants effect at the air-water interface: a biophysical approach to membrane peroxidation. FEBS Journal, 279, 219-219. DOI:
Garcia, B; Magalhaes, J; Fregapane, G; Salvador, MD; Paiva-Martins, F. 2012. Potential of selected Portuguese cultivars for the production of high quality monovarietal virgin olive oil. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 114, 1070-1082. DOI: 10.1002/ejlt.201200046
Pinheiro, M; Lucio, M; Reis, S; Lima, JLFC; Caio, JM; Moiteiro, C; Martin-Romero, MT; Camacho, L; Giner-Casares, JJ. 2012. Molecular Interaction of Rifabutin on Model Lung Surfactant Monolayers. JOURNAL OF PHYSICAL CHEMISTRY B, 116, 11635-11645. DOI: 10.1021/jp303725j
Salaun, P; Gibbon-Walsh, KB; Alves, GMS; Soares, HMVM; van den Berg, CMG. 2012. Determination of arsenic and antimony in seawater by voltammetric and chronopotentiometric stripping using a vibrated gold microwire electrode. ANALYTICA CHIMICA ACTA, 746, 53-62. DOI: 10.1016/j.aca.2012.08.013
Pinto, ISS; Soares, HMVM. 2012. Selective leaching of molybdenum from spent hydrodesulphurisation catalysts using ultrasound and microwave methods. HYDROMETALLURGY, 129, 19-25. DOI: 10.1016/j.hydromet.2012.08.008
Pereira-Leite, C; Nunes, C; Lima, JLFC; Reis, S; Lucio, M. 2012. Interaction of Celecoxib with Membranes: The Role of Membrane Biophysics on its Therapeutic and Toxic Effects. JOURNAL OF PHYSICAL CHEMISTRY B, 116, 13608-13617. DOI: 10.1021/jp304037v
Santos, JR; Sarraguca, MC; Rangel, AOSS; Lopes, JA. 2012. Evaluation of green coffee beans quality using near infrared spectroscopy: A quantitative approach. FOOD CHEMISTRY, 135, 1828-1835. DOI: 10.1016/j.foodchem.2012.06.059
Sousa, CCS; Morais, VMF; Matos, MAR. 2013. Experimental and computational thermochemistry of 6,7-dihydro-4(5H)-benzofuranone. JOURNAL OF CHEMICAL THERMODYNAMICS, 56, 83-88. DOI: 10.1016/j.jct.2012.07.008
Bueno, PR; Goncalves, LM; dos Santos, FC; dos Santos, ML; Barros, AA; Faria, RC. 2013. Electrogravimetric Analysis by Quartz-Crystal Microbalance on the Consumption of the Neurotransmitter Acetylcholine by Acetylcholinesterase. ANALYTICAL LETTERS, 46, 258-265. DOI: 10.1080/00032719.2012.713065
Sousa, TFA; Amorim, CG; Montenegro, MCBSM; Araujo, AN. 2013. Cyclodextrin based potentiometric sensor for determination of ibuprofen in pharmaceuticals and waters. SENSORS AND ACTUATORS B-CHEMICAL, 176, 660-666. DOI: 10.1016/j.snb.2012.09.016
Nunes, C; Sousa, CT; Proenca, MP; Apolinario, A; Lima, JLFC; Reis, S; Araujo, JP; Lucio, M. 2013. Synchrotron small angle X-ray scattering for the evaluation of the interaction of silica nanotubes with lipid membranes. RSC Advances, 3, 10323-10328. DOI: 10.1039/c3ra22974b
Silva, JG; Tavares, EM; Goncalves, LM; Valente, IM; Carvalho, DO; Rodrigues, JA. 2013. Voltammetric Analysis of Licochalcone A in Licorice. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 160, H671-H673. DOI: 10.1149/2.020310jes
Santos, CM; Valente, IM; Goncalves, LM; Rodrigues, JA. 2013. Chromatographic analysis of methylglyoxal and other alpha-dicarbonyls using gas-diffusion microextraction. ANALYST, 138, 7233-7237. DOI: 10.1039/c3an00766a
Queiros, RB; Gouveia, C; Fernandes, JRA; Marques, PVS; Noronha, JP; Sales, MGF; Jorge, PAS. 2013. A LONG PERIOD GRATING-BASED PLATFORM FOR THE DETECTION OF E. COLI PROTEINS. COLLOIDAL QUANTUM DOTS/NANOCRYSTALS FOR BIOMEDICAL APPLICATIONS VI, 8785. DOI: 10.1117/12.2025811
Santos, CMM; Garcia, MBQ; Silva, AMS; Santus, R; Morliere, P; Fernandes, E. 2013. Electrochemical characterization of bioactive hydroxyxanthones by cyclic voltammetry. TETRAHEDRON LETTERS, 54, 85-90. DOI: 10.1016/j.tetlet.2012.10.103
Valente, IM; Santos, CM; Moreira, MM; Rodrigues, JA. 2013. New application of the QuEChERS methodology for the determination of volatile phenols in beverages by liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1271, 27-32. DOI: 10.1016/j.chroma.2012.11.026
Alves, GMS; Magalhaes, JMCS; Soares, HMVM. 2013. Voltammetric Quantification of Zn and Cu, Together with Hg and Pb, Based on a Gold Microwire Electrode, in a Wider Spectrum of Surface Waters. ELECTROANALYSIS, 25, 493-502. DOI: 10.1002/elan.201200518
Pinheiro, M; Giner-Casares, JJ; Lucio, M; Caio, JM; Moiteiro, C; Lima, JLFC; Reis, S; Camacho, L. 2013. Interplay of mycolic acids, antimycobacterial compounds and pulmonary surfactant membrane: A biophysical approach to disease. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1828, 896-905. DOI: 10.1016/j.bbamem.2012.09.015
Passos, MLC; Lima, JLFC; Saraiva, MLMFS. 2013. Laccase-biosilica nanostructures - A miniaturized automatic approach. CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 91, 113-119. DOI: 10.1139/cjc-2012-0193
Paiga, P; Santos, LHMLM; Amorim, CG; Araujo, AN; Montenegro, MCBSM; Pena, A; Delerue-Matos, C. 2013. Pilot monitoring study of ibuprofen in surface waters of north of Portugal. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 20, 2410-2420. DOI: 10.1007/s11356-012-1128-1
Vaz, M; Meirinhos-Soares, L; Sousa, CCS; Ramirez, M; Melo-Cristino, J; Lopes, JA. 2013. Serotype discrimination of encapsulated Streptococcus pneumoniae strains by Fourier-transform infrared spectroscopy and chemometrics. JOURNAL OF MICROBIOLOGICAL METHODS, 93, 102-107. DOI: 10.1016/j.mimet.2013.02.008
Pascoa, RNMJ; Magalhaes, LM; Lopes, JA. 2013. FT-NIR spectroscopy as a tool for valorization of spent coffee grounds: Application to assessment of antioxidant properties. FOOD RESEARCH INTERNATIONAL, 51, 579-586. DOI: 10.1016/j.foodres.2013.01.035
Alves, GMS; Magalhaes, JMCS; Soares, HMVM. 2013. Simultaneous Determination of Nickel and Cobalt Using a Solid Bismuth Vibrating Electrode by Adsorptive Cathodic Stripping Voltammetry. ELECTROANALYSIS, 25, 1247-1255. DOI: 10.1002/elan.201200643
Toth, IV; Santos, IC; Azevedo, CFM; Fernandes, JES; Pascoa, RNMJ; Mesquita, RBR; Rangel, AOSS. 2013. Flow-Injection Spectrophotometric Determination of Bromate in Bottled Drinking Water Samples Using Chlorpromazine Reagent and a Liquid Waveguide Capillary Cell. ANALYTICAL SCIENCES, 29, 563-570. DOI:
Skraskova, K; Santos, LHMLM; Satinsky, D; Pena, A; Montenegro, MCBSM; Solich, P; Novakova, L. 2013. Fast and sensitive UHPLC methods with fluorescence and tandem mass spectrometry detection for the determination of tetracycline antibiotics in surface waters. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 927, 201-208. DOI: 10.1016/j.jchromb.2012.12.032
Sarraguca, MC; Santos, JR; Rangel, AOSS; Lopes, JA. 2013. Authenticity Control of Roasted Coffee Brands Using Near-Infrared Spectroscopy. Food Analytical Methods, 6, 892-899. DOI: 10.1007/s12161-012-9499-y
Novais, A; Vuotto, C; Pires, J; Montenegro, C; Donelli, G; Coque, TM; Peixe, L. 2013. Diversity and biofilm-production ability among isolates of Escherichia coli phylogroup D belonging to ST69, ST393 and ST405 clonal groups. BMC MICROBIOLOGY, 13. DOI: 10.1186/1471-2180-13-144
Santos, LHMLM; Paiga, P; Araujo, AN; Pena, A; Delerue-Matos, C; Montenegro, MCBSM. 2013. Development of a simple analytical method for the simultaneous determination of paracetamol, paracetamol-glucuronide and p-aminophenol in river water. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 930, 75-81. DOI: 10.1016/j.jchromb.2013.04.032
Cuartero, M; Amorim, CG; Araujo, AN; Ortuno, JA; Montenegro, MCBSM. 2013. A SO2-selective electrode based on a Zn-porphyrin for wine analysis. ANALYTICA CHIMICA ACTA, 787, 57-63. DOI: 10.1016/j.aca.2013.05.038
Pinto, ISS; Soares, HMVM. 2013. Recovery of molybdates from an alkaline leachate of spent hydrodesulphurisation catalyst - proposal of a nearly-closed process. JOURNAL OF CLEANER PRODUCTION, 52, 481-487. DOI: 10.1016/j.jclepro.2013.03.021
Soares, EV; Soares, HMVM. 2013. Cleanup of industrial effluents containing heavy metals: a new opportunity of valorising the biomass produced by brewing industry. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 97, 6667-6675. DOI: 10.1007/s00253-013-5063-y
Alves, GMS; Magalhaes, JMCS; Tauler, R; Soares, HMVM. 2013. Simultaneous Anodic Stripping Voltammetric Determination of Pb and Cd, Using a Vibrating Gold Microwire Electrode, Assisted by Chemometric Techniques. ELECTROANALYSIS, 25, 1895-1906. DOI: 10.1002/elan.201300198
Teixeira, J; Ferraz, P; Almeida, A; Verde, N; Fidalgo, F. 2013. Metallothionein multigene family expression is differentially affected by Chromium (III) and (VI) in Solanum nigrum L. plants. FOOD AND ENERGY SECURITY, 2, 130-140. DOI: 10.1002/fes3.26
Santos, LHMLM; Gros, M; Rodriguez-Mozaz, S; Delerue-Matos, C; Pena, A; Barcelo, D; Montenegro, MCBSM. 2013. Contribution of hospital effluents to the load of pharmaceuticals in urban wastewaters: Identification of ecologically relevant pharmaceuticals. SCIENCE OF THE TOTAL ENVIRONMENT, 461, 302-316. DOI: 10.1016/j.scitotenv.2013.04.077
Machado, CMM; Alves, GMS; Pinto, ISS; Scheerlinck, S; Van Acker, S; Soares, HMVM. 2013. Modelling and Optimization of Stability Constants of Cadmium or Zinc with Biological Buffers (DIPSO or TAPS) in Aqueous Solutions by Electrochemical Techniques. JOURNAL OF SOLUTION CHEMISTRY, 42, 1602-1619. DOI: 10.1007/s10953-013-0063-1
Oliveira, HM; Segundo, MA; Fonseca, AJM; Cabrita, ARJ. 2013. Combining Ultrasound-Assisted Extraction and a Microliter Colorimetric Assay for the Streamlined Determination of Urea in Animal Feedstuff. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 61, 9602-9608. DOI: 10.1021/jf403037y
Rosende, M; Magalhaes, LM; Segundo, MA; Miro, M. 2013. Automated Microdialysis-Based System for in Situ Microsampling and Investigation of Lead Bioavailability in Terrestrial Environments under Physiologically Based Extraction Conditions. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 47, 11668-11675. DOI: 10.1021/es401872j
Eliat-Eliat, M; Pinto, ISS; Alves, GMS; Olle, V; Soares, HMVM. 2013. Determination of the stability constants of Pb-(DIPSO)(x)-(OH)(y) and Pb-(AMPSO)(x)-(OH)(y) systems. JOURNAL OF COORDINATION CHEMISTRY, 66, 3544-3560. DOI: 10.1080/00958972.2013.842641
Castro, CM; Pinheiro, M; Lucio, M; Giner-Casares, JJ; Camacho, L; Lima, JLFC; Reis, S; Segundo, MA. 2013. Insights about alpha-tocopherol and Trolox interaction with phosphatidylcholine monolayers under peroxidation conditions through Brewster angle microscopy. COLLOIDS AND SURFACES B-BIOINTERFACES, 111, 626-635. DOI: 10.1016/j.colsurfb.2013.06.043
Ribeiro, DSM; Marques, KL; Santos, JLM; Prior, JAV. 2013. Automatic multiple photodegradation unit on a multipumping flow system: Monitoring of ketoprofen. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 271, 77-84. DOI: 10.1016/j.jphotochem.2013.08.008
dos Santos, CAT; Lopo, M; Pascoa, RNMJ; Lopes, JA. 2013. A Review on the Applications of Portable Near-Infrared Spectrometers in the Agro-Food Industry. APPLIED SPECTROSCOPY, 67, 1215-1233. DOI: 10.1366/13-07228
Pinto, ISS; Soares, HMVM. 2013. Microwave-assisted selective leaching of nickel from spent hydrodesulphurization catalyst: A comparative study between sulphuric and organic acids. HYDROMETALLURGY, 140, 20-27. DOI: 10.1016/j.hydromet.2013.08.009
Moreira, MM; Morais, S; Carvalho, DO; Barros, AA; Delerue-Matos, C; Guido, LF. 2013. Brewer's spent grain from different types of malt: Evaluation of the antioxidant activity and identification of the major phenolic compounds. FOOD RESEARCH INTERNATIONAL, 54, 382-388. DOI: 10.1016/j.foodres.2013.07.023
Sousa, C; Novais, A; Magalhaes, A; Lopes, J; Peixe, L. 2013. Diverse high-risk B2 and D Escherichia coli clones depicted by Fourier Transform Infrared Spectroscopy. Scientific Reports, 3. DOI: 10.1038/srep03278
Sousa, CCS; Matos, MAR; Santos, LMNBF; Morais, VMF. 2013. Energetics of 2-and 3-coumaranone isomers: A combined calorimetric and computational study. JOURNAL OF CHEMICAL THERMODYNAMICS, 67, 210-216. DOI: 10.1016/j.jct.2013.08.012
Melo, T; Santos, N; Lopes, D; Alves, E; Maciel, E; Faustino, MAF; Tome, JPC; Neves, MGPMS; Almeida, A; Domingues, P; Segundo, MA; Domingues, MRM. 2013. Photosensitized oxidation of phosphatidylethanolamines monitored by electrospray tandem mass spectrometry. JOURNAL OF MASS SPECTROMETRY, 48, 1357-1365. DOI: 10.1002/jms.3301
Ramos, P; Santos, A; Pinto, NR; Mendes, R; Magalhaes, T; Almeida, A. 2014. Iron levels in the human brain: A post-mortem study of anatomical region differences and age-related changes. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 28, 13-17. DOI: 10.1016/j.jtemb.2013.08.001
Santos, S; Neto, IFF; Machado, MD; Soares, HMVM; Soares, EV. 2014. Siderophore Production by Bacillus megaterium: Effect of Growth Phase and Cultural Conditions. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 172, 549-560. DOI: 10.1007/s12010-013-0562-y
Matias, R; Ribeiro, PRS; Sarraguca, MC; Lopes, JA. 2014. A UV spectrophotometric method for the determination of folic acid in pharmaceutical tablets and dissolution tests. Analytical Methods, 6, 3065-3071. DOI: 10.1039/c3ay41874j
Carvalho, MM; Ribeiro, DSM; Santos, JLM; Prior, JAV. 2014. pH-sensitive spectrophotometric control of nilutamide in an automatic micro-flow system. NEW JOURNAL OF CHEMISTRY, 38, 2856-2864. DOI: 10.1039/c4nj00158c
Rodrigues, SSM; Oleksiak, Z; Ribeiro, DSM; Pobozy, E; Trojanowicz, M; Prior, JAV; Santos, JLM. 2014. Selective determination of sulphide based on photoluminescence quenching of MPA-capped CdTe nanocrystals by exploiting a gas-diffusion multi-pumping flow method. Analytical Methods, 6, 7956-7966. DOI: 10.1039/c4ay01823k
Moura, CC; Segundo, MA; das Neves, J; Reis, S; Sarmento, B. 2014. Co-association of methotrexate and SPIONs into anti-CD64 antibody-conjugated PLGA nanoparticles for theranostic application. International Journal of Nanomedicine, 9, 4911-4922. DOI: 10.2147/IJN.S68440
Valente, IM; Ramos, RM; Goncalves, LM; Rodrigues, JA. 2014. Determination of ethyl carbamate in spirits using salting-out assisted liquid-liquid extraction and high performance liquid chromatography with fluorimetric detection. Analytical Methods, 6, 9136-9141. DOI: 10.1039/c4ay02075h
Ferreira, CMH; Pinto, ISS; Alves, GMS; Sedeghi, SM; Soares, HMVM. 2014. Aqueous complexation studies of lead(II) and cadmium(II) with 1,3-bis(tris(hydroxymethyl)methylamino)propane pH buffer. JOURNAL OF COORDINATION CHEMISTRY, 67, 3354-3370. DOI: 10.1080/00958972.2014.963570
Sramkova, I; Amorim, CG; Sklenarova, H; Montenegro, MCBM; Horstkotte, B; Araujo, AN; Solich, P. 2014. Fully automated analytical procedure for propofol determination by sequential injection technique with spectrophotometric and fluorimetric detections. TALANTA, 118, 104-110. DOI: 10.1016/j.talanta.2013.09.059
Magalhaes, LM; Ramos, II; Reis, S; Segundo, MA. 2014. Antioxidant profile of commercial oenological tannins determined by multiple chemical assays. AUSTRALIAN JOURNAL OF GRAPE AND WINE RESEARCH, 20, 72-79. DOI: 10.1111/ajgw.12058
da Silva, H; Pacheco, JG; Magalhaes, JMCS; Viswanathan, S; Delerue-Matos, C. 2014. MIP-graphene-modified glassy carbon electrode for the determination of trimethoprim. BIOSENSORS & BIOELECTRONICS, 52, 56-61. DOI: 10.1016/j.bios.2013.08.035
Correia, H; Ramos, P; Santos, A; Pinto, NR; Mendes, R; Magalhaes, T; Almeida, A. 2014. A post-mortem study of the anatomical region differences and age-related changes on Ca and Mg levels in the human brain. MICROCHEMICAL JOURNAL, 113, 69-76. DOI: 10.1016/j.microc.2013.11.012
Magalhaes, LM; Barreiros, L; Reis, S; Segundo, MA. 2014. Kinetic matching approach applied to ABTS assay for high-throughput determination of total antioxidant capacity of food products. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 33, 187-194. DOI: 10.1016/j.jfca.2014.01.003
Catelani, TA; Toth, IV; Lima, JLFC; Pezza, L; Pezza, HR. 2014. A simple and rapid screening method for sulfonamides in honey using a flow injection system coupled to a liquid waveguide capillary cell. TALANTA, 121, 281-287. DOI: 10.1016/j.talanta.2013.12.034
Sousa, C; Silva, L; Grosso, F; Lopes, J; Peixe, L. 2014. Development of a FTIR-ATR based model for typing clinically relevant Acinetobacter baumannii clones belonging to ST98, ST103, ST208 and ST218. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 133, 108-114. DOI: 10.1016/j.jphotobio1.2014.02.015
Barrado, E; Couto, RAS; Quinaz, MB; Lima, JLFC; Castrillejo, Y. 2014. Electrochemical behaviour of ferrocene in the ionic liquid 1-ethyl-3-methylimidazolium tetrafluoroborate, EMIMBF4, at 298 K. JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 720, 139-146. DOI: 10.1016/j.jelechem.2014.03.026
Sousa, TFA; Aniceto, MC; Amorim, CG; Souto-Lopes, M; Perez-Mongiovi, D; Montenegro, MCBSM; Araujo, AN. 2014. Vortex-assisted liquid-liquid micro-extraction and high-performance liquid chromatography for a higher sensitivity methyl methacrylate determination in biological matrices. BIOMEDICAL CHROMATOGRAPHY, 28, 680-685. DOI: 10.1002/bmc.3089
Rodrigues, SSM; Ribeiro, DSM; Molina-Garcia, L; Medina, AR; Prior, JAV; Santos, JLM. 2014. Fluorescence enhancement of CdTe MPA-capped quantum dots by glutathione for hydrogen peroxide determination. TALANTA, 122, 157-165. DOI: 10.1016/j.talanta.2014.01.031
Sousa, C; Grosso, F; Meirinhos-Soares, L; Peixe, L; Lopes, J. 2014. Identification of carbapenem-resistant Acinetobacter baumannii clones using infrared spectroscopy. Journal of Biophotonics, 7, 287-294. DOI: 10.1002/jbio.201200075
Couto, CMCM; Pinto, I; Madureira, TV; Rocha, MJ; Tiritan, ME; Lopes, JA; Almeida, AA. 2014. LOWER DOURO RIVER BASIN (PORTUGAL) WATER QUALITY - FOCUS ON TRACE ELEMENT CHANGES AND ANTHROPOGENIC SOURCES OF CONTAMINATION. Global NEST Journal, 16, 252-268. DOI:
Pinto, E; Almeida, AA; Aguiar, AARM; Ferreira, IMPLVO. 2014. Changes in macrominerals, trace elements and pigments content during lettuce (Lactuca sativa L.) growth: Influence of soil composition. FOOD CHEMISTRY, 152, 603-611. DOI: 10.1016/j.foodchem.2013.12.023
Sousa, CCS; Matos, MAR; Santos, LMNBF; Morais, VMF. 2014. Energetics of 2- and 3-coumaranone isomers: A combined calorimetric and computational study (Reprinted from J. Chem. Thermodynamics, vol 67, pg 210-216, 2013). JOURNAL OF CHEMICAL THERMODYNAMICS, 73, 283-289. DOI: 10.1016/j.jct.2014.03.017
Sousa, CCS; Matos, MAR; Morais, VMF. 2014. Energetics and stability of azulene: From experimental thermochemistry to high-level quantum chemical calculations. JOURNAL OF CHEMICAL THERMODYNAMICS, 73, 101-109. DOI: 10.1016/j.jct.2013.11.008
Ramos, II; Maia, MA; Reis, S; Magalhaes, LM; Segundo, MA. 2014. Lab-on-valve combined with a kinetic-matching approach for fast evaluation of total antioxidant capacity in wines. Analytical Methods, 6, 3622-3628. DOI: 10.1039/c3ay42185f
Sousa, C; Botelho, J; Silva, L; Grosso, F; Nemec, A; Lopes, J; Peixe, L. 2014. MALDI-TOF MS and chemometric based identification of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex species. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY, 304, 669-677. DOI: 10.1016/j.ijmm.2014.04.014
Marques, SS; Magalhaes, LM; Toth, IV; Segundo, MA. 2014. Insights on Antioxidant Assays for Biological Samples Based on the Reduction of Copper Complexes-The Importance of Analytical Conditions. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 15, 11387-11402. DOI: 10.3390/ijms150711387
Novais, A; Sousa, C; Caballero, JD; Fernandez-Olmos, A; Lopes, J; Ramos, H; Coque, TM; Canton, R; Peixe, L. 2014. MALDI-TOF mass spectrometry as a tool for the discrimination of high-risk Escherichia coli clones from phylogenetic groups B2 (ST131) and D (ST69, ST405, ST393). EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 33, 1391-1399. DOI: 10.1007/s10096-014-2071-5
Sousa, C; Silva, L; Grosso, F; Nemec, A; Lopes, J; Peixe, L. 2014. Discrimination of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex species by Fourier transform infrared spectroscopy. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 33, 1345-1353. DOI: 10.1007/s10096-014-2078-y
Sarraguca, MC; Ribeiro, PRS; Santos, AO; Silva, MCD; Lopes, JA. 2014. A PAT approach for the on-line monitoring of pharmaceutical co-crystals formation with near infrared spectroscopy. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 471, 478-484. DOI: 10.1016/j.ijpharm.2014.06.003
Rosende, M; Magalhaes, LM; Segundo, MA; Miro, M. 2014. Assessing oral bioaccessibility of trace elements in soils under worst-case scenarios by automated in-line dynamic extraction as a front end to inductively coupled plasma atomic emission spectrometry. ANALYTICA CHIMICA ACTA, 842, 1-10. DOI: 10.1016/j.aca.2014.06.033
Branquinho, R; Sousa, C; Lopes, J; Pintado, ME; Peixe, LV; Osorio, H. 2014. Differentiation of Bacillus pumilus and Bacillus safensis Using MALDI-TOF-MS. PLoS One, 9. DOI: 10.1371/journal.pone.0110127
Ramos, P; Santos, A; Pinto, NR; Mendes, R; Magalhaes, T; Almeida, A. 2014. Anatomical Region Differences and Age-Related Changes in Copper, Zinc, and Manganese Levels in the Human Brain. BIOLOGICAL TRACE ELEMENT RESEARCH, 161, 190-201. DOI: 10.1007/s12011-014-0093-6
Sasaki, MK; Ribeiro, DSM; Frigerio, C; Prior, JAV; Santos, JLM; Zagatto, EAG. 2014. Chemiluminometric determination of ascorbic acid in pharmaceutical formulations exploiting photo-activation of GSH-capped CdTe quantum dots. LUMINESCENCE, 29, 901-907. DOI: 10.1002/bio.2639
Branquinho, R; Sousa, C; Osorio, H; Meirinhos-Soares, L; Lopes, J; Carrico, JA; Busse, HJ; Abdulmawjood, A; Klein, G; Kampfer, P; Pintado, ME; Peixe, LV. 2014. Bacillus invictae sp nova, isolated from a health product. INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 64, 3867-3876. DOI: 10.1099/ijs.0.067850-0
Pinto, MF; Moura, CC; Nunes, C; Segundo, MA; Lima, SAC; Reis, S. 2014. A new topical formulation for psoriasis: Development of methotrexate-loaded nanostructured lipid carriers. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 477, 519-526. DOI: 10.1016/j.ijpharm.2014.10.067
Rebelo, A; Pinto, E; Silva, MV; Almeida, AA. 2015. Chemical safety of children's play paints: Focus on selected heavy metals. MICROCHEMICAL JOURNAL, 118, 203-210. DOI: 10.1016/j.microc.2014.09.008
Sadeghi, SM; Ferreira, CMH; Vandenbogaerde, S; Soares, HMVM. 2015. Graphic data analysis and complex formation curves as modeling and optimization tools for characterization of Cu-(buffer)(x)-(OH)(y) systems involving BTP or BES in aqueous solution. JOURNAL OF COORDINATION CHEMISTRY, 68, 777-793. DOI: 10.1080/00958972.2014.1000317
Silva, NFD; Magalhaes, JMCS; Oliva-Teles, MT; Delerue-Matos, C. 2015. A potentiometric magnetic immunoassay for rapid detection of Salmonella typhimurium. Analytical Methods, 7, 4008-4011. DOI: 10.1039/c5ay00053j
Gomes, A; Capela, JP; Ribeiro, D; Freitas, M; Silva, AMS; Pinto, DCGA; Santos, CMM; Cavaleiro, JAS; Lima, JLFC; Fernandes, E. 2015. Inhibition of NF-kB Activation and Cytokines Production in THP-1 Monocytes by 2-Styrylchromones. Medicinal Chemistry, 11, 560-566. DOI:
Lopo, M; dos Santos, CAT; Pascoa, RNMJ; Graca, AR; Lopes, JA. 2015. Non-invasive real-time monitoring of vineyard soils, berries and leaves with FT-NIR spectroscopy. 38TH WORLD CONGRESS OF VINE AND WINE (PART 1), 5. DOI: 10.1051/bioconf/20150501003
Grosso, F; Silva, L; Sousa, C; Ramos, H; Quinteira, S; Peixe, L. 2015. Extending the reservoir of bla (IMP-5): the emerging pathogen Acinetobacter bereziniae. Future Microbiology, 10, 1609-1613. DOI: 10.2217/fmb.15.88
Pinto, ISS; Sadeghi, SM; Soares, HMVM. 2015. Separation and recovery of nickel, as a salt, from an EDTA leachate of spent hydrodesulphurization catalyst using precipitation methods. CHEMICAL ENGINEERING SCIENCE, 122, 130-137. DOI: 10.1016/j.ces.2014.09.012
Passos, MLC; Costa, D; Lima, JLFC; Saraiva, MLMFS. 2015. Sequential injection technique as a tool for the automatic synthesis of silver nanoparticles in a greener way. TALANTA, 133, 45-51. DOI: 10.1016/j.talanta.2014.04.089
Pinto, E; Almeida, AA; Aguiar, AA; Ferreira, IMPLVO. 2015. Comparison between the mineral profile and nitrate content of microgreens and mature lettuces. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 37, 38-43. DOI: 10.1016/j.jfca.2014.06.018
Santos, A; Ramos, P; Fernandes, L; Magalhaes, T; Almeida, A; Sousa, A. 2015. Firing distance estimation based on the analysis of GSR distribution on the target surface using ICP-MS-An experimental study with a 7.65 mm x 17 mm Browning pistol (.32 ACP). FORENSIC SCIENCE INTERNATIONAL, 247, 62-68. DOI: 10.1016/j.forsciint.2014.12.006
Ramos, P; Santos, A; Pinto, NR; Mendes, R; Magalhaes, T; Almeida, A. 2015. Anatomical Regional Differences in Selenium Levels in the Human Brain. BIOLOGICAL TRACE ELEMENT RESEARCH, 163, 89-96. DOI: 10.1007/s12011-014-0160-z
Botelho, J; Grosso, F; Sousa, C; Peixe, L. 2015. Characterization of a new genetic environment associated with GES-6 carbapenemase from a Pseudomonas aeruginosa isolate belonging to the high-risk clone ST235. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 70, 615-617. DOI: 10.1093/jac/dku391
Pinto, E; Almeida, AA; Ferreira, IMPLVO. 2015. Assessment of metal(loid)s phytoavailability in intensive agricultural soils by the application of single extractions to rhizosphere soil. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 113, 418-424. DOI: 10.1016/j.ecoenv.2014.12.026
Rodrigues, SSM; Prieto, DR; Ribeiro, DSM; Barrado, E; Prior, JAV; Santos, JLM. 2015. Competitive metal-ligand binding between CdTe quantum dots and EDTA for free Ca2+ determination. TALANTA, 134, 173-182. DOI: 10.1016/j.talanta.2014.11.008
Pascoa, RNMJ; Machado, S; Magalhaes, LM; Lopes, JA. 2015. Value Adding to Red Grape Pomace Exploiting Eco-friendly FT-NIR Spectroscopy Technique. Food and Bioprocess Technology, 8, 865-874. DOI: 10.1007/s11947-014-1454-z
Neves, AR; Reis, S; Segundo, MA. 2015. Development and Validation of a HPLC Method Using a Monolithic Column for Quantification of trans-Resveratrol in Lipid Nanoparticles for Intestinal Permeability Studies. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 63, 3114-3120. DOI: 10.1021/acs.jafc.5b00390
Sousa, C; Botelho, J; Grosso, F; Silva, L; Lopes, J; Peixe, L. 2015. Unsuitability of MALDI-TOF MS to discriminate Acinetobacter baumannii clones under routine experimental conditions. Frontiers in Microbiology, 6. DOI: 10.3389/fmicb.2015.00481
Pinto, E; Soares, C; Couto, CMCM; Almeida, A. 2015. y TRACE ELEMENTS IN AMBIENT AIR AT PORTO METROPOLITAN AREA-CHECKING FOR COMPLIANCE WITH NEW EUROPEAN UNION (EU) AIR QUALITY STANDARDS. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 78, 848-859. DOI: 10.1080/15287394.2015.1051177
Ribeiro, D; Freitas, M; Lima, JLFC; Fernandes, E. 2015. Proinflammatory Pathways: The Modulation by Flavonoids. MEDICINAL RESEARCH REVIEWS, 35, 877-936. DOI: 10.1002/med.21347
Marques, SS; Magalhaes, LM; Mota, AIP; Soares, TRP; Korsak, B; Reis, S; Segundo, MA. 2015. Myoglobin microplate assay to evaluate prevention of protein peroxidation. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 114, 305-311. DOI: 10.1016/j.jpba.2015.06.006
Gil, R; Amorim, CG; Crombie, L; Lin, PKT; Araujo, A; Montenegro, MDC. 2015. Study of a Novel Bisnaphthalimidopropyl Polyamine as Electroactive Material for Perchlorate-selective Potentiometric Sensors. ELECTROANALYSIS, 27, 2809-2819. DOI: 10.1002/elan.201500275
Alves, AC; Ramos, II; Nunes, C; Magalhaes, LM; Sklenarova, H; Segundo, MA; Lima, JLFC; Reis, S. 2016. On-line automated evaluation of lipid nanoparticles transdermal permeation using Franz diffusion cell and low-pressure chromatography. TALANTA, 146, 369-374. DOI: 10.1016/j.talanta.2015.08.070
Marques, SS; Toth, IV; Magalhaes, LM; Reis, S; Segundo, MA. 2016. High-sensitivity programmable flow method for assessment of total antioxidant capacity in biological samples. MICROCHEMICAL JOURNAL, 124, 261-266. DOI: 10.1016/j.microc.2015.09.001
Zelena, L; Marques, SS; Segundo, MA; Miro, M; Pavek, P; Sklenarova, H; Solich, P. 2016. Fully automatic flow-based device for monitoring of drug permeation across a cell monolayer. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 408, 971-981. DOI: 10.1007/s00216-015-9194-0
Peixoto, PS; Toth, IV; Segundo, MA; Lima, JLFC. 2016. Fluoroquinolones and sulfonamides: features of their determination in water. A review. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 96, 185-202. DOI: 10.1080/03067319.2015.1128539
Ferraz, R; Noronha, J; Murtinheira, F; Nogueira, F; Machado, M; Prudencio, M; Parapini, S; D'Alessandro, S; Teixeira, C; Gomes, A; Prudencio, C; Gomes, P. 2016. Primaquine-based ionic liquids as a novel class of antimalarial hits. RSC Advances, 6, 56134-56138. DOI: 10.1039/c6ra10759a
Ribeiro, CMR; Maia, AS; Ribeiro, AR; Couto, C; Almeida, AA; Santos, M; Tiritan, ME. 2016. Anthropogenic pressure in a Portuguese river: Endocrine-disrupting compounds, trace elements and nutrients. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 51, 1043-1052. DOI: 10.1080/10934529.2016.1198622
Ramdzan, AN; Barreiros, L; Almeida, MIGS; Kolev, SD; Segundo, MA. 2016. Determination of salivary cotinine through solid phase extraction using a bead-injection lab-on-valve approach hyphenated to hydrophilic interaction liquid chromatography. JOURNAL OF CHROMATOGRAPHY A, 1429, 284-291. DOI: 10.1016/j.chroma.2015.12.051
Mendes, M; Carvalho, AP; Magalhaes, JMCS; Moreira, M; Guido, L; Gomes, AM; Delerue-Matos, C. 2016. Response surface evaluation of microwave-assisted extraction conditions for Lycium barbarum bioactive compounds. Innovative Food Science & Emerging Technologies, 33, 319-326. DOI: 10.1016/j.ifset.2015.12.025
Segundo, MA; Abreu, VLRG; Osorio, MV; Nogueira, S; Lin, PKT; Cordeiro-da-Silva, A; Lima, SAC. 2016. Development and validation of HPLC method with fluorometric detection for quantification of bisnaphthalimidopropyldiaminooctane in animal tissues following administration in polymeric nanoparticles. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 120, 290-296. DOI: 10.1016/j.jpba.2015.12.033
Melo, T; Domingues, P; Ferreira, R; Milic, I; Fedorova, M; Santos, SM; Segundo, MA; Domingues, MRM. 2016. Recent Advances on Mass Spectrometry Analysis of Nitrated Phospholipids. ANALYTICAL CHEMISTRY, 88, 2622-2629. DOI: 10.1021/acs.analchem.5b03407
Neves, AR; Martins, S; Segundo, MA; Reis, S. 2016. Nanoscale Delivery of Resveratrol towards Enhancement of Supplements and Nutraceuticals. Nutrients, 8. DOI: 10.3390/nu8030131
Costa, LF; Fonseca, BM; Amaral, C; Mendes, A; Braga, J; Teixeira, NA; Correia-da-Silva, G. 2016. Cannabinoid signaling in human placenta: effects of cannabinoids in cytotrophoblast cells. MEDICINE, 95. DOI:
Barreiros, L; Queiroz, JF; Magalhaes, LM; Silva, AMT; Segundo, MA. 2016. Analysis of 17-beta-estradiol and 17-alpha-ethinylestradiol in biological and environmental matrices - A review. MICROCHEMICAL JOURNAL, 126, 243-262. DOI: 10.1016/j.microc.2015.12.003
Moreira, NFF; Sousa, JM; Macedo, G; Ribeiro, AR; Barreiros, L; Pedrosa, M; Faria, JL; Pereira, MFR; Castro-Silva, S; Segundo, MA; Manaia, CM; Nunes, OC; Silva, AMT. 2016. Photocatalytic ozonation of urban wastewater and surface water using immobilized TiO2 with LEDs: Micropollutants, antibiotic resistance genes and estrogenic activity. WATER RESEARCH, 94, 10-22. DOI: 10.1016/j.watres.2016.02.003
Napoleao, DC; Pinheiro, RB; Zaidan, LEMC; Rodriguez-Diaz, JM; Araujo, AD; Montenegro, MD; da Silva, VL. 2016. Validation of a chromatographic method for amoxicillin determination in wastewaters after its degradation by advanced oxidation process. Desalination and Water Treatment, 57, 10988-10994. DOI: 10.1080/19443994.2015.1043652
Pasion, R; Paiva, TO; Pedrosa, P; Gaspar, H; Vasconcelos, B; Martins, AC; Amaral, MH; Nobrega, JM; Pascoa, R; Fonseca, C; Barbosa, F. 2016. Assessing a novel polymer-wick based electrode for EEG neurophysiological research. JOURNAL OF NEUROSCIENCE METHODS, 267, 126-131. DOI: 10.1016/j.jneumeth.2016.04.009
Pascoa, RNMJ; Lopo, M; dos Santos, CAT; Graca, AR; Lopes, JA. 2016. Exploratory study on vineyards soil mapping by visible/near-infrared spectroscopy of grapevine leaves. COMPUTERS AND ELECTRONICS IN AGRICULTURE, 127, 15-25. DOI: 10.1016/j.compag.2016.05.014
Da Silva, DD; Ferreira, A; Martins, M; Valente, M; Remiao, F; Carvalho, F; Bastos, M; Carmo, H. 2016. In vitro neurotoxicity of 'Legal X': The combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl) piperazine (TFMPP) induces mitochondrial impairment and disrupts thiol homeostasis in dopaminergic SH-SY5Y cells. TOXICOLOGY LETTERS, 258, S247-S247. DOI: 10.1016/j.toxlet.2016.06.1877
Ferreira, A; Ponte, F; Silva, R; Pereira, CR; Sousa, E; Pinto, M; Bastos, M; Remiao, F. 2016. 1-(Propan-2-ylamino)-4-propoxy-9h-thioxanthen-9-one (TX5), a newly synthetized P-glycoprotein activator: In vivo study and method development and validation for biological samples quantification. TOXICOLOGY LETTERS, 258, S184-S185. DOI: 10.1016/j.toxlet.2016.06.1681
Silva, EMP; Barros, CMRF; Santos, CMM; Barros, AS; Domingues, MRM; Silva, AMS. 2016. Characterization of 2,3-diarylxanthones by electrospray mass spectrometry: gas-phase chemistry versus known antioxidant activity properties. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 30, 2228-2236. DOI: 10.1002/rcm.7697
Silva, EMP; Melo, T; Sousa, BC; Resende, DISP; Magalhaes, LM; Segundo, MA; Silva, AMS; Domingues, MRM. 2016. Do cinnamylideneacetophenones have antioxidant properties and a protective effect toward the oxidation of phosphatidylcholines?. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 121, 331-337. DOI: 10.1016/j.ejmech.2016.05.040
Ferreira, M; Silva, E; Barreiros, L; Segundo, MA; Lima, SAC; Reis, S. 2016. Methotrexate loaded lipid nanoparticles for topical management of skin-related diseases: Design, characterization and skin permeation potential. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 512, 14-21. DOI: 10.1016/j.ijpharm.2016.08.008
Cunha-Reis, C; Machado, A; Barreiros, L; Araujo, F; Nunes, R; Seabra, V; Ferreira, D; Segundo, MA; Sarmento, B; das Neves, J. 2016. Nanoparticles-in-film for the combined vaginal delivery of anti-HIV microbicide drugs. JOURNAL OF CONTROLLED RELEASE, 243, 43-53. DOI: 10.1016/j.jconrel.2016.09.020
Machado, J; Azevedo, J; Freitas, M; Pinto, E; Almeida, A; Vasconcelos, V; Campos, A. 2017. Analysis of the use of microcystin-contaminated water in the growth and nutritional quality of the root-vegetable, Daucus carota. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 24, 752-764. DOI: 10.1007/s11356-016-7822-7
Zaidan, LEMC; Rodriguez-Diaz, JM; Napoleao, DC; Montenegro, MDBDD; Araujo, AD; Benachour, M; Silva, VL. 2017. Heterogeneous photocatalytic degradation of phenol and derivatives by (BiPO4/H2O2/UV and TiO2/H2O2/UV) and the evaluation of plant seed toxicity tests. KOREAN JOURNAL OF CHEMICAL ENGINEERING, 34, 511-522. DOI: 10.1007/s11814-016-0293-1
dos Santos, CAT; Pascoa, RNMJ; Lopes, JA. 2017. A review on the application of vibrational spectroscopy in the wine industry: From soil to bottle. TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 88, 100-118. DOI: 10.1016/j.trac.2016.12.012
Barreiros, L; Cunha-Reis, C; Silva, EMP; Carvalho, JRB; das Neves, J; Sarmento, B; Segundo, MA. 2017. Development and validation of a liquid chromatography-MS/MS method for simultaneous quantification of tenofovir and efavirenz in biological tissues and fluids. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 136, 120-125. DOI: 10.1016/j.jpba.2016.12.028
Silva, E; Barreiros, L; Segundo, MA; Lima, SAC; Reis, S. 2017. Cellular interactions of a lipid-based nanocarrier model with human keratinocytes: Unravelling transport mechanisms. Acta Biomaterialia, 53, 439-449. DOI: 10.1016/j.actbio.2017.01.057
Maia, MA; Soares, TRP; Mota, AIP; Rosende, M; Magalhaes, LM; Miro, M; Segundo, MA. 2017. Dynamic flow-through approach to evaluate readily bioaccessible antioxidants in solid food samples. TALANTA, 166, 162-168. DOI: 10.1016/j.talanta.2017.01.040
Alves, AC; Ribeiro, D; Horta, M; Lima, JLFC; Nunes, C; Reis, S. 2017. The daunorubicin interplay with mimetic model membranes of cancer cells: A biophysical interpretation. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1859, 941-948. DOI: 10.1016/j.bbamem.2017.01.034
Melo, T; Domingues, P; Ribeiro-Rodrigues, TM; Girao, H; Segundo, MA; Domingues, MRM. 2017. Characterization of phospholipid nitroxidation by LC-MS in biomimetic models and in,H9c2 Myoblast using a lipidomic approach. FREE RADICAL BIOLOGY AND MEDICINE, 106, 219-227. DOI: 10.1016/j.freeradbiomed.2017.02.033
Araujo, D; Freitas, F; Sevrin, C; Grandfils, C; Reis, MAM. 2017. Co-production of chitin-glucan complex and xylitol by Komagataella pastoris using glucose and xylose mixtures as carbon source. CARBOHYDRATE POLYMERS, 166, 24-30. DOI: 10.1016/j.carbpol.2017.02.088
Alves, AC; Magarkar, A; Horta, M; Lima, JLFC; Bunker, A; Nunes, C; Reis, S. 2017. Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies. Scientific Reports, 7. DOI: 10.1038/s41598-017-06445-z
Chaves, LL; Lima, SAC; Vieira, ACC; Barreiros, L; Segundo, MA; Ferreira, D; Sarmento, B; Reis, S. 2017. pH-sensitive nanoparticles for improved oral delivery of dapsone: risk assessment, design, optimization and characterization. Nanomedicine, 12, 1975-1990. DOI: 10.2217/nnm-2017-0105
Alves, AC; Ribeiro, D; Horta, M; Lima, JLFC; Nunes, C; Reis, S. 2017. A biophysical approach to daunorubicin interaction with model membranes: relevance for the drug's biological activity. Journal of the Royal Society Interface, 14. DOI: 10.1098/rsif.2017.0408
Silva, EMP; Barreiros, L; Sa, P; Afonso, C; Kozek-Langenecker, S; Segundo, MA. 2017. Analytical methods for quantification of tranexamic acid in biological fluids: A review. MICROCHEMICAL JOURNAL, 134, 333-342. DOI: 10.1016/j.microc.2017.06.020
Cruz, MV; Sarraguca, MC; Freitas, F; Lopes, JA; Reis, MAM. 2015. Online monitoring of P(3HB) produced from used cooking oil with near-infrared spectroscopy. JOURNAL OF BIOTECHNOLOGY, 194, 1-9. DOI: 10.1016/j.jbiotec.2014.11.022
Diniz, MS; Salgado, R; Pereira, VJ; Carvalho, G; Oehmen, A; Reis, MAM; Noronha, JP. 2015. Ecotoxicity of ketoprofen, diclofenac, atenolol and their photolysis byproducts in zebrafish (Danio rerio). SCIENCE OF THE TOTAL ENVIRONMENT, 505, 282-289. DOI: 10.1016/j.scitotenv.014.09.103
Pinto, ISS; Ascenso, OS; Barros, MT; Soares, HMVM. 2015. Pre-treatment of the paper pulp in the bleaching process using biodegradable chelating agents. International Journal of Environmental Science and Technology, 12, 975-982. DOI: 10.1007/s13762-013-0480-0
Moreira, MA; Andre, LC; Ribeiro, AB; da Silva, MDRG; Cardeal, ZL. 2015. Quantitative Analysis of Endocrine Disruptors by Comprehensive Two-Dimensional Gas Chromatography. JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY, 26, 531-536. DOI: 10.5935/0103-5053.20150006
Pereira, JA; Pessoa, AM; Cordeiro, MNDS; Fernandes, R; Prudencio, C; Noronha, JP; Vieira, M. 2015. Quinoxaline, its derivatives and applications: A State of the Art review. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 96, 664-672. DOI: 10.1016/j.ejmech.2014.06.058
Pinto, MI; Salgado, R; Cottrell, BA; Cooper, WJ; Burrows, HD; Vale, C; Sontag, G; Noronha, JP. 2015. Influence of dissolved organic matter on the photodegradation and volatilization kinetics of chlorpyrifos in coastal waters. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 310, 189-196. DOI: 10.1016/j.jphotochem.2015.05.024
Cruz, MV; Araujo, D; Alves, VD; Freitas, F; Reis, MAM. 2016. Characterization of medium chain length polyhydroxyalkanoate produced from olive oil deodorizer distillate. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 82, 243-248. DOI: 10.1016/j.ijbiomac.2015.10.043
Lima, C; Madureira, J; Melo, R; Carolino, MM; Noronha, JP; Margaca, FMA; Verde, SC. 2016. Biodegradation Bench Study of Cork Wastewater using Gamma Radiation. JOURNAL OF ADVANCED OXIDATION TECHNOLOGIES, 19, 73-78. DOI:
Porfirio, S; Calado, ML; Noceda, C; Cabrita, MJ; da Silva, MG; Azadi, P; Peixe, A. 2016. Tracking biochemical changes during adventitious root formation in olive (Olea europaea L.). SCIENTIA HORTICULTURAE, 204, 41-53. DOI: 10.1016/j.scienta.2016.03.029
das Neves, J; Cunha-Reis, C; Barreiros, L; Machado, A; Araujo, F; Nunes, R; Segundo, MA; Sarmento, B. 2016. Pharmacokinetics and Safety of Vaginal Tenofovir/Efavirenz-loaded Nanoparticles-in-Film in Mice. AIDS RESEARCH AND HUMAN RETROVIRUSES, 32, 220-220. DOI:
Salgado, R; Noronha, JP; Oehmen, A; Carvalho, G; Reis, MAM. 2010. Analysis of 65 pharmaceuticals and personal care products in 5 wastewater treatment plants in Portugal using a simplified analytical methodology. WATER SCIENCE AND TECHNOLOGY, 62, 2862-2871. DOI: 10.2166/wst.2010.985
Mateus, E; Barata, RC; Zrostlikova, J; da Silva, MDRG; Paiva, MR. 2010. Characterization of the volatile fraction emitted by Pinus spp. by one- and two-dimensional chromatographic techniques with mass spectrometric detection. JOURNAL OF CHROMATOGRAPHY A, 1217, 1845-1855. DOI: 10.1016/j.chroma.2010.01.045
Queiros, RB; Noronha, JP; Sales, MGF; Aguilar, GG. 2010. Sensors for the Detection and Quantification of Bacterial Contamination in Water for Human Use. ADVANCED ENGINEERING MATERIALS, 12, B175-B178. DOI: 10.1002/adem.200980029
Silveira, CM; Gomes, SP; Araujo, AN; Montenegro, MCBSM; Todorovic, S; Viana, AS; Silva, RJC; Moura, JJG; Almeida, MG. 2010. An efficient non-mediated amperometric biosensor for nitrite determination. BIOSENSORS & BIOELECTRONICS, 25, 2026-2032. DOI: 10.1016/j.bios.2010.01.031
Mateus, EP; Zrostlikova, J; da Silva, MDRG; Ribeiro, AB; Marriott, P. 2010. Electrokinetic removal of creosote from treated timber waste: a comprehensive gas chromatographic view. JOURNAL OF APPLIED ELECTROCHEMISTRY, 40, 1183-1193. DOI: 10.1007/s10800-010-0089-7
Santos, PMP; Antunes, AMM; Noronha, J; Fernandes, E; Vieira, AJSC. 2010. Scavenging activity of aminoantipyrines against hydroxyl radical. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 45, 2258-2264. DOI: 10.1016/j.ejmech.2010.01.071
Carvalho, G; Marques, Ri; Lopes, AR; Faria, C; Noronha, JP; Oehmen, A; Nunes, OC; Reis, MAM. 2010. Biological treatment of propanil and 3,4-dichloroaniline: Kinetic and microbiological characterisation. WATER RESEARCH, 44, 4980-4991. DOI: 10.1016/j.watres.2010.08.006
Martins, JG; Gameiro, P; Barros, MT; Soares, HMVM. 2010. Potentiometric and UV-Visible Spectroscopic Studies of Cobalt(II), Copper(II), and Nickel(II) Complexes with N,N '-(S,S)-Bis[1-carboxy-2-(imidazol-4-yl)ethyl]ethylenediamine. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 55, 3410-3417. DOI: 10.1021/je1001494
Martins, JG; Pinto, RM; Gameiro, P; Barros, MT; Soares, HMVM. 2010. Aqueous Equilibrium and Solution Structural Studies of the Interaction of N,N'-bis(4-imidazolymethyl)etylenediamine with Ca(II), Cd(II), Co(II), Cu(II), Mg(II), Mn(II), Ni(II), Pb(II) and Zn(II) Metal Ions. JOURNAL OF SOLUTION CHEMISTRY, 39, 1153-1167. DOI: 10.1007/s10953-010-9569-y
Pinto, MI; Sontag, G; Bernardino, RJ; Noronha, JP. 2010. Pesticides in water and the performance of the liquid-phase microextraction based techniques. A review. MICROCHEMICAL JOURNAL, 96, 225-237. DOI: 10.1016/j.microc.2010.06.010
Lanham, AB; Carvalheira, M; Rodrigues, AM; Cardoso, VV; Benoliel, MJ; Barros, MT; Morgado, MJ; Soares, HMVM; Lemos, PC; Reis, MAM. 2011. Ethylenediamine-N,N '-diglutaric acid (EDDG) as a promising biodegradable chelator: Quantification, complexation and biodegradation. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 46, 553-559. DOI: 10.1080/10934529.2011.562805
Melo, CI; Bogel-Lukasik, R; da Silva, MG; Bogel-Lukasik, E. 2011. Advantageous heterogeneously catalysed hydrogenation of carvone with supercritical carbon dioxide. GREEN CHEMISTRY, 13, 2825-2830. DOI: 10.1039/c1gc15495h
da Silva, MDRG; Pereira, MMA. 2011. New chiral imidazolium ionic liquids from isomannide. CARBOHYDRATE RESEARCH, 346, 197-202. DOI: 10.1016/j.carres.2010.11.011
Martins, JG; Barros, MT; Pinto, RM; Soares, HMVM. 2011. Cadmium(II), Lead(II), and Zinc(II) Ions Coordination of N,N '-(S,S)Bis[1-carboxy-2-(imidazol-4yl)ethyl]ethylenediamine: Equilibrium and Structural Studies. JOURNAL OF CHEMICAL AND ENGINEERING DATA, 56, 398-405. DOI: 10.1021/je1007718
Rodrigues, AR; Paiva, A; da Silva, MG; Simoes, P; Barreiros, S. 2011. Continuous enzymatic production of biodiesel from virgin and waste sunflower oil in supercritical carbon dioxide. JOURNAL OF SUPERCRITICAL FLUIDS, 56, 259-264. DOI: 10.1016/j.supflu.2010.10.031
Barroso, MF; Noronha, JP; Delerue-Matos, C; Oliveira, MBPP. 2011. Flavored Waters: Influence of Ingredients on Antioxidant Capacity and Terpenoid Profile by HS-SPME/GC-MS. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 59, 5062-5072. DOI: 10.1021/jf1048244
Torres, MP; Cabrita, MJ; Da Silva, MDRG; Palma, V; Freitas, AMC. 2011. THE IMPACT OF MALOLACTIC FERMENTATION ON THE VOLATILE COMPOSITION OF THE TRINCADEIRA WINE VARIETY. JOURNAL OF FOOD BIOCHEMISTRY, 35, 898-913. DOI: 10.1111/j.1745-4514.2010.00424.x
Ferraz, R; Branco, LC; Prudencio, C; Noronha, JP; Petrovski, Z. 2011. Ionic Liquids as Active Pharmaceutical Ingredients. ChemMedChem, 6, 975-985. DOI: 10.1002/cmdc.201100082
Salgado, R; Marques, R; Noronha, JP; Mexia, JT; Carvalho, G; Oehmen, A; Reis, MAM. 2011. Assessing the diurnal variability of pharmaceutical and personal care products in a full-scale activated sludge plant. ENVIRONMENTAL POLLUTION, 159, 2359-2367. DOI: 10.1016/j.envpol.2011.07.004
Cabrita, MJ; Aires-De-Sousa, J; Da Silva, MDRG; Rei, F; Freitas, AMC. 2012. Multivariate statistical approaches for wine classification based on low molecular weight phenolic compounds. AUSTRALIAN JOURNAL OF GRAPE AND WINE RESEARCH, 18, 138-146. DOI: 10.1111/j.1755-0238.2012.00182.x
Martins, N; Garcia, R; Da Silva, MC; Cabrita, MJ. 2012. VOLATILE COMPOUNDS FROM OAK, CHERRY, CHESTNUT AND ACACIA CHIPS: INFLUENCE OF TOASTING LEVEL. Ciencia e Tecnica Vitivinicola, 27, 49-57. DOI:
Salgado, R; Marques, R; Noronha, JP; Carvalho, G; Oehmen, A; Reis, MAM. 2012. Assessing the removal of pharmaceuticals and personal care products in a full-scale activated sludge plant. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 19, 1818-1827. DOI: 10.1007/s11356-011-0693-z
Salgado, R; Oehmen, A; Carvalho, G; Noronha, JP; Reis, MAM. 2012. Biodegradation of clofibric acid and identification of its metabolites. JOURNAL OF HAZARDOUS MATERIALS, 241, 182-189. DOI: 10.1016/j.jhazmat.2012.09.029
Oehmen, A; Marques, Ri; Noronha, JP; Carvalho, G; Reis, MAM. 2013. Propionate addition enhances the biodegradation of the xenobiotic herbicide propanil and its metabolite. BIORESOURCE TECHNOLOGY, 127, 195-201. DOI: 10.1016/j.biortech.2012.09.120
Salgado, R; Pereira, VJ; Carvalho, G; Soeiro, R; Gaffney, V; Almeida, C; Cardoso, VV; Ferreira, E; Benoliel, MJ; Ternes, TA; Oehmen, A; Reis, MAM; Noronha, JP. 2013. Photodegradation kinetics and transformation products of ketoprofen, diclofenac and atenolol in pure water and treated wastewater. JOURNAL OF HAZARDOUS MATERIALS, 244, 516-527. DOI: 10.1016/j.jhazmat.2012.10.039
Silva, R; Folgosa, F; Soares, P; Pereira, AS; Garcia, R; Gestal-Otero, JJ; Tavares, P; da Silva, MDRG. 2013. Occupational cosmic radiation exposure in Portuguese airline pilots: study of a possible correlation with oxidative biological markers. RADIATION AND ENVIRONMENTAL BIOPHYSICS, 52, 211-220. DOI: 10.1007/s00411-013-0460-2
Ruivo, A; Ventura, MG; da Silva, MDRG; Laia, CAT. 2013. Synthesis of gold nanoparticles in sol-gel glass porogens containing [bmim][BF4] ionic liquid. JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY, 68, 234-244. DOI: 10.1007/s10971-013-3159-6
Costa, N; Matos, S; da Silva, MDRG; Pereira, MMA. 2013. Cyclodextrin-Based Ionic Liquids as Enantioselective Stationary Phases in Gas Chromatography. ChemPlusChem, 78, 1466-1474. DOI: 10.1002/cplu.201300229
Pinto, MI; Vale, C; Sontag, G; Noronha, JP. 2013. Effects of ultrasonic irradiation and direct heating on extraction of priority pesticides from marine sediments. INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 93, 1638-1659. DOI: 10.1080/03067319.2013.831409
Vieira, M; Pinheiro, C; Fernandes, R; Noronha, JP; Prudencio, C. 2014. Antimicrobial activity of quinoxaline 1,4-dioxide with 2-and 3-substituted derivatives. MICROBIOLOGICAL RESEARCH, 169, 287-293. DOI: 10.1016/j.micres.2013.06.015
Martins, JG; Neto, IFF; Pinto, ISS; Soares, EV; Barros, MT; Soares, HMVM. 2014. Alternative chelating agents: Evaluation of the ready biodegradability and complexation properties. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART A-TOXIC/HAZARDOUS SUBSTANCES & ENVIRONMENTAL ENGINEERING, 49, 344-354. DOI: 10.1080/10934529.2014.846706
Neto, IFF; Pinto, ISS; Barros, MT; Maycock, CD; Soares, HMVM. 2014. Study of the Performance of Nitrilotriacetic Acid and Ethylenediiminopropanedioic Acid as Alternative Biodegradable Chelating Agents for Pulp Bleaching. International Journal of Environmental Research, 8, 613-620. DOI:
Pinto, MI; Micaelo, C; Vale, C; Sontag, G; Noronha, JP. 2014. Screening of Priority Pesticides in Ulva sp. Seaweeds by Selective Pressurized Solvent Extraction Before Gas Chromatography with Electron Capture Detector Analysis. ARCHIVES OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 67, 547-556. DOI: 10.1007/s00244-014-0038-2
Ferreira, CMH; Pinto, ISS; Soares, EV; Soares, HMVM. 2015. (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review. RSC Advances, 5, 30989-31003. DOI: 10.1039/c4ra15453c
Ferreira, RC; Ramos, RM; Goncalves, LM; Almeida, PJ; Rodrigues, JA. 2015. Application of gas-diffusion microextraction to solid samples using the chromatographic determination of alpha-diketones in bread as a case study. ANALYST, 140, 3648-3653. DOI: 10.1039/c5an00196j
Rodrigues, SSM; Ribeiro, DSM; Frigerio, C; Costa, SPF; Prior, JAV; Pinto, PCAG; Santos, JLM; Saraiva, MLMFS; Passos, MLC. 2015. Immobilization of Distinctly Capped CdTe Quantum Dots onto Porous Aminated Solid Supports. CHEMPHYSCHEM, 16, 1880-1888. DOI: 10.1002/cphc.201500159
Rodrigues, DMC; Ribeiro, DSM; Frigerio, C; Rodrigues, SSM; Santos, JLM; Prior, JAV. 2015. Antioxidant capacity automatic assay based on inline photogenerated radical species from L-glutathione-capped CdTe quantum dots. TALANTA, 141, 220-229. DOI: 10.1016/j.talanta.2015.04.013
Couto, RAS; Lima, JLFC; Quinaz, MB. 2015. Screen-printed Electrode Based Electrochemical Sensor for the Detection of Isoniazid in Pharmaceutical Formulations and Biological Fluids. International Journal of Electrochemical Science, 10, 8738-8749. DOI:
Fernandes, DM; Silva, N; Pereira, C; Moura, C; Magalhaes, JMCS; Bachiller-Baeza, B; Rodriguez-Ramos, I; Guerrero-Ruiz, A; Delerue-Matos, C; Freire, C. 2015. MnFe2O4@CNT-N as novel electrochemical nanosensor for determination of caffeine, acetaminophen and ascorbic acid. SENSORS AND ACTUATORS B-CHEMICAL, 218, 128-136. DOI: 10.1016/j.snb.2015.05.003
Tournour, HH; Segundo, MA; Magalhaes, LM; Barreiros, L; Queiroz, J; Cunha, LM. 2015. Valorization of grape pomace: Extraction of bioactive phenolics with antioxidant properties. INDUSTRIAL CROPS AND PRODUCTS, 74, 397-406. DOI: 10.1016/j.indcrop.2015.05.055
Sarraguca, MC; Ribeiro, PRS; Dos Santos, AO; Lopes, JA. 2015. Batch Statistical Process Monitoring Approach to a Cocrystallization Process. JOURNAL OF PHARMACEUTICAL SCIENCES, 104, 4099-4108. DOI: 10.1002/jps.24623
Pinto, ISS; Sadeghi, SM; Izatt, NE; Soares, HMVM. 2015. Recovery of metals from an acid leachate of spent hydrodesulphurization catalyst using molecular recognition technology. CHEMICAL ENGINEERING SCIENCE, 138, 353-362. DOI: 10.1016/j.ces.2015.08.018
Couto, RAS; Lima, JLFC; Quinaz, MB. 2016. Recent developments, characteristics and potential applications of screen-printed electrodes in pharmaceutical and biological analysis. TALANTA, 146, 801-814. DOI: 10.1016/j.talanta.2015.06.011
de Souza, GCS; Ribeiro, DSM; Rodrigues, SSM; Paim, APS; Lavorante, AF; da Silva, VL; Santos, JLM; Araujo, AN; Montenegro, MCBSM. 2016. Clean photoinduced generation of free reactive oxygen species by silica films embedded with CdTe-MTA quantum dots. RSC Advances, 6, 8563-8571. DOI: 10.1039/c5ra23133g
Ribeiro, AB; Chiste, RC; Lima, JLFC; Fernandes, E. 2016. Solanum diploconos fruits: profile of bioactive compounds and in vitro antioxidant capacity of different parts of the fruit. Food & Function, 7, 2249-2257. DOI: 10.1039/c6fo00326e
Sarraguca, JMG; Lima, C; Machado, F; Lopes, JA; Almeida, A; Fernandes, L; Magalhaes, T; Santos, A. 2016. A FT-NIR spectroscopy methodology to estimate firing distance based on the direct analysis of the bullet impact surface. ANALYST, 141, 4410-4416. DOI: 10.1039/c6an00247a
Silva, S; Tobaldini-Valerio, F; Costa-de-Oliveira, S; Henriques, M; Azeredo, J; Ferreira, EC; Lopes, JA; Sousa, C. 2016. Discrimination of clinically relevant Candida species by Fourier-transform infrared spectroscopy with attenuated total reflectance (FTIR-ATR). RSC Advances, 6, 92065-92072. DOI: 10.1039/c6ra16769a
Ramos, P; Santos, A; Pinto, E; Pinto, NR; Mendes, R; Magalhaes, T; Almeida, A. 2016. Alkali metals levels in the human brain tissue: Anatomical region differences and age-related changes. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 38, 174-182. DOI: 10.1016/j.jtemb.2016.03.018
Magalhaes, LM; Machado, S; Segundo, MA; Lopes, JA; Pascoa, RNMJ. 2016. Rapid assessment of bioactive phenolics and methylxanthines in spent coffee grounds by FT-NIR spectroscopy. TALANTA, 147, 460-467. DOI: 10.1016/j.talanta.2015.10.022
Osorio, MV; Marques, SS; Oliveira, HM; Barreiros, L; Segundo, MA. 2016. Fluorometric method based on molecular recognition solid-phase extraction for determination of riboflavin in milk and infant formula. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 45, 141-146. DOI: 10.1016/j.jfca.2015.10.007
Ramos, RM; Goncalves, LM; Vyskocil, V; Rodrigues, JA. 2016. Free sulphite determination in wine using screen-printed carbon electrodes with prior gas-diffusion microextraction. ELECTROCHEMISTRY COMMUNICATIONS, 63, 52-55. DOI: 10.1016/j.elecom.2015.12.010
dos Santos, CAT; Pascoa, RNMJ; Porto, PALS; Cerdeira, AL; Lopes, JA. 2016. Application of Fourier-transform infrared spectroscopy for the determination of chloride and sulfate in wines. LWT-FOOD SCIENCE AND TECHNOLOGY, 67, 181-186. DOI: 10.1016/j.lwt.2015.11.050
Ramos, II; Gregorio, BJR; Barreiros, L; Magalhaes, LM; Toth, IV; Reis, S; Lima, JLFC; Segundo, MA. 2016. Programmable flow system for automation of oxygen radical absorbance capacity assay using pyrogallol red for estimation of antioxidant reactivity. TALANTA, 150, 599-606. DOI: 10.1016/j.talanta.2015.12.061
Pinto, E; Almeida, A; Ferreira, IMPLVO. 2016. Essential and non-essential/toxic elements in rice available in the Portuguese and Spanish markets. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 48, 81-87. DOI: 10.1016/j.jfca.2016.02.008
Lopo, M; Pascoa, RNMJ; Graca, AR; Lopes, JA. 2016. Classification of Vineyard Soils Using Portable and Benchtop Near-Infrared Spectrometers: A Comparative Study. SOIL SCIENCE SOCIETY OF AMERICA JOURNAL, 80, 652-661. DOI: 10.2136/sssaj2015.09.0324
Neto, IFF; Sousa, CA; Brito, MSCA; Futuro, AM; Soares, HMVM. 2016. A simple and nearly-closed cycle process for recycling copper with high purity from end life printed circuit boards. SEPARATION AND PURIFICATION TECHNOLOGY, 164, 19-27. DOI: 10.1016/j.seppur.2016.03.007
Carvalho, AP; Mendes, M; Moreira, MM; Cruz, D; Magalhaes, JMCS; Barroso, MF; Ramalhosa, MJ; Duarte, A; Guido, L; Gomes, AM; Matos, CD. 2016. Microwave-assisted extraction in goji berries: effect on composition and bioactivity, evaluated through conventional and nonconventional methodologies. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 51, 1401-1408. DOI: 10.1111/ijfs.13105
Couto, RAS; Quinaz, MB. 2016. Development of a Nafion/MWCNT-SPCE-Based Portable Sensor for the Voltammetric Analysis of the Anti-Tuberculosis Drug Ethambutol. SENSORS, 16. DOI: 10.3390/s16071015
Sarraguca, MC; Paisana, M; Pinto, J; Lopes, JA. 2016. Real-time monitoring of cocrystallization processes by solvent evaporation: A near infrared study. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 90, 76-84. DOI: 10.1016/j.ejps.2015.12.025
de Assis, SGF; de Andrade, MF; Montenegro, MCBSM; dos Reis, BF; Paim, APS. 2016. Determination of Polyphenol Content by Formation of Unstable Compound Using a Mini-Pump Multicommutation System. Food Analytical Methods, 9, 2261-2269. DOI: 10.1007/s12161-016-0411-z
Silva, L; Grosso, F; Branquinho, R; Ribeiro, TG; Sousa, C; Peixe, L. 2016. Exploring non-hospital-related settings in Angola reveals new Acinetobacter reservoirs for bla(OXA-23) and bla(OXA-58). INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 48, 228-230. DOI: 10.1016/j.ijantimicag.2016.06.003
Carqueijeiro, I; Guimaraes, AL; Bettencourt, S; Martinez-Cortes, T; Guedes, JG; Gardner, R; Lopes, T; Andrade, C; Bispo, C; Martins, NP; Andrade, P; Valentao, P; Valente, IM; Rodrigues, JA; Duarte, P; Sottomayor, M. 2016. Isolation of Cells Specialized in Anticancer Alkaloid Metabolism by Fluorescence-Activated Cell Sorting. PLANT PHYSIOLOGY, 171, 2371-2378. DOI: 10.1104/pp.16.01028
Vieira, EF; Carvalho, J; Pinto, E; Cunha, S; Almeida, AA; Ferreira, IMPLVO. 2016. Nutritive value, antioxidant activity and phenolic compounds profile of brewer's spent yeast extract. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, 52, 44-51. DOI: 10.1016/j.jfca.2016.07.006
Ferreira, A; Fernandes, I; Alves, C; Mateus, N; Gomes, P; Vale, N. 2016. DEVELOPMENT OF NEW PEPTIDE-GEMCITABINE CONJUGATES FOR CANCER. JOURNAL OF PEPTIDE SCIENCE, 22, S108-S108. DOI:
Santos, JR; Viegas, O; Pascoa, RNMJ; Ferreira, IMPLVO; Rangel, AOSS; Lopes, JA. 2016. In-line monitoring of the coffee roasting process with near infrared spectroscopy: Measurement of sucrose and colour. FOOD CHEMISTRY, 208, 103-110. DOI: 10.1016/j.foodchem.2016.03.114
Couto, D; Freitas, M; Costa, VM; Chiste, RC; Almeida, A; Lopez-Quintela, MA; Rivas, J; Freitas, P; Silva, P; Carvalho, F; Fernandes, E. 2016. Biodistribution of polyacrylic acid-coated iron oxide nanoparticles is associated with proinflammatory activation and liver toxicity. JOURNAL OF APPLIED TOXICOLOGY, 36, 1321-1331. DOI: 10.1002/jat.3323
Cabrita, ARJ; Maia, MRG; Oliveira, HM; Sousa-Pinto, I; Almeida, AA; Pinto, E; Fonseca, AJM. 2016. Tracing seaweeds as mineral sources for farm-animals. JOURNAL OF APPLIED PHYCOLOGY, 28, 3135-3150. DOI: 10.1007/s10811-016-0839-y
Sarraguca, MC; Matias, R; Figueiredo, R; Ribeiro, PRS; Martins, AT; Lopes, JA. 2016. Near infrared spectroscopy to monitor drug release in-situ during dissolution tests. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 513, 1-7. DOI: 10.1016/j.ijpharm.2016.09.010
Martins, M; Mourato, C; Sanches, S; Noronha, JP; Crespo, MTB; Pereira, IAC. 2017. Biogenic platinum and palladium nanoparticles as new catalysts for the removal of pharmaceutical compounds. WATER RESEARCH, 108, 160-168. DOI: 10.1016/j.watres.2016.10.071
Guzman-Guillen, R; Campos, A; Machado, J; Freitas, M; Azevedo, J; Pinto, E; Almeida, A; Camean, AM; Vasconcelos, V. 2017. Effects of Chrysosporum (Aphanizomenon) ovalisporum extracts containing cylindrospermopsin on growth, photosynthetic capacity, and mineral content of carrots (Daucus carota). ECOTOXICOLOGY, 26, 22-31. DOI: 10.1007/s10646-016-1737-4
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Rodrigues, C; Novais, A; Sousa, C; Ramos, H; Coque, TM; Canton, R; Lopes, JA; Peixe, L. 2017. Elucidating constraints for differentiation of major human Klebsiella pneumoniae clones using MALDI-TOF MS. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 36, 379-386. DOI: 10.1007/s10096-016-2812-8
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Brandao, PF; Ramos, RM; Almeida, PJ; Rodrigues, JA. 2017. Determination of Carbonyl Compounds in Cork Agglomerates by GDME-HPLC-UV: Identification of the Extracted Compounds by HPLC-MS/MS. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 65, 1037-1042. DOI: 10.1021/acs.jafc.6b05370
Ribeiro, DSM; de Souza, GCS; Melo, A; Soares, JX; Rodrigues, SSM; Araujo, AN; Montenegro, MCBSM; Santos, JLM. 2017. Synthesis of distinctly thiol-capped CdTe quantum dots under microwave heating: multivariate optimization and characterization. JOURNAL OF MATERIALS SCIENCE, 52, 3208-3224. DOI: 10.1007/s10853-016-0610-4
Pinto, E; Cruz, M; Ramos, P; Santos, A; Almeida, A. 2017. Metals transfer from tobacco to cigarette smoke: Evidences in smokers' lung tissue. JOURNAL OF HAZARDOUS MATERIALS, 325, 31-35. DOI: 10.1016/j.jhazmat.2016.11.069
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Catelani, T; Pascoa, R; Santos, JR; Pezza, L; Pezza, H; Lima, JLFC; Lopes, JA. 2017. A Non-invasive Real-Time Methodology for the Quantification of Antioxidant Properties in Coffee During the Roasting Process Based on Near-Infrared Spectroscopy. Food and Bioprocess Technology, 10, 630-638. DOI: 10.1007/s11947-016-1843-6
Alves, CM; Ferreira, CMH; Soares, EV; Soares, HMVM. 2017. A multi-metal risk assessment strategy for natural freshwater ecosystems based on the additive inhibitory free metal ion concentration index. ENVIRONMENTAL POLLUTION, 223, 517-523. DOI: 10.1016/j.envpol.2017.01.053
Brandao, PF; Ramos, RM; Valente, IM; Almeida, PJ; Carro, AM; Lorenzo, RA; Rodrigues, JA. 2017. Gas-diffusion microextraction coupled with spectrophotometry for the determination of formaldehyde in cork agglomerates. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409, 2885-2892. DOI: 10.1007/s00216-017-0233-x
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Brandao, E; Silva, MS; Garcia-Estevez, I; Mateus, N; de Freitas, V; Soares, S. 2017. Molecular study of mucin-procyanidin interaction by fluorescence quenching and Saturation Transfer Difference (STD)-NMR. FOOD CHEMISTRY, 228, 427-434. DOI: 10.1016/j.foodchem.2017.02.027
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Cordeiro, T; Castineira, C; Mendes, D; Danede, F; Sotomayor, J; Fonseca, IM; da Silva, MG; Paiva, A; Barreiros, S; Cardoso, MM; Viciosa, MT; Correia, NT; Dionisio, M. 2017. Stabilizing Unstable Amorphous Menthol through Inclusion in Mesoporous Silica Hosts. MOLECULAR PHARMACEUTICS, 14, 3164-3177. DOI: 10.1021/acs.molpharmaceut.7b00386
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Rebelo, TSCR; Noronha, JP; Galesio, M; Santos, H; Diniz, M; Sales, MGF; Fernandes, MH; Costa-Rodrigues, J. 2016. Testing the variability of PSA expression by different human prostate cancer cell lines by means of a new potentiometric device employing molecularly antibody assembled on graphene surface. Materials Science & Engineering C-Materials for Biological Applications, 59, 1069-1078. DOI: 10.1016/j.msec.2015.11.032
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