Integrative Structural Biology tools for the study of protein-ligand interactions
The course took place at FCT-Universidade NOVA de Lisboa, in the campus of Caparica, Portugal, from 13-19 July 2015
OBJECTIVE OF THE COURSE: to illustrate the added value of a structural biology approach to the study of protein-ligand interactions by combining core methodologies, X-ray Crystallography, NMR, EPR, Carbohydrate Microarrays, ITC and Molecular Modeling from a hands-on perspective, giving emphasis to their limitations and complementarities.
To achieve this, and to better illustrate the integrative context, the students received training by working in a study-case, a protein that recognizes and binds to carbohydrates, which will be the focus of the several complementary methodologies. Besides the hands-on training there was theory lectures where the main theoretical aspects of each technique was explained always with an emphasis on the complementarity with the other techniques.
Supported by: INSTRUCT, COST, UCIBIO-REQUIMTE at FCT-UNL
Course Details & Registration: