Ana Luísa Carvalho

Independent Researcher

Assistant Investigator (since 2003)
Personal Website
Phone number
+351212948300 (ext: 10940)
Researcher ID

Main publications

  • Ribeiro, Diana O., Benedita A. Pinheiro, Ana Luisa Carvalho, and Angelina S. Palma. 2018. Targeting protein-carbohydrate interactions in plant cell-wall biodegradation: the power of carbohydrate microarrays. Carbohydrate Chemistry: Chemical and Biological Approaches Volume 43, 43, DOI: 10.1039/9781788010641-00159
  • Gomes, Ana Sara, Filipa Trovão, Benedita Andrade Pinheiro, Filipe Freire, Sara Gomes, Carla Oliveira, Lucília Domingues, Maria João Romão, Lucília Saraiva, and Ana Luísa Carvalho. 2018. The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(1184), DOI: 10.3390/ijms19041184
  • dos Santos, R; Carvalho, AL; Roque, ACA. 2017. Renaissance of protein crystallization and precipitation in biopharmaceuticals purification. BIOTECHNOLOGY ADVANCES, 35, DOI: 10.1016/j.biotechadv.2016.11.005
  • Bule, P; Alves, VD; Israeli-Ruimy, V; Carvalho, AL; Ferreira, LMA; Smith, SP; Gilbert, HJ; Najmudin, S; Bayer, EA; Fontes, CMGA. 2017. Assembly of Ruminococcus flavefaciens cellulosome revealed by structures of two cohesin-dockerin complexes. Scientific Reports, 7, DOI: 10.1038/s41598-017-00919-w
  • Bras, JLA; Pinheiro, BA; Cameron, K; Cuskin, F; Viegas, A; Najmudin, S; Bule, P; Pires, VMR; Romao, MJ; Bayer, EA; Spencer, HL; Smith, S; Gilbert, HJ; Alves, VD; Carvalho, AL; Fontes, CMGA. 2016. Diverse specificity of cellulosome attachment to the bacterial cell surface. Scientific Reports, 6, DOI: 10.1038/srep38292
  • Ribeiro, D; Kulakova, A; Quaresma, P; Pereira, E; Bonifacio, C; Romao, MJ; Franco, R; Carvalho, AL. 2014. Use of Gold Nanoparticles as Additives in Protein Crystallization. CRYSTAL GROWTH & DESIGN, 14, DOI: 10.1021/cg4014398

Main research interests

  • Functional and structural characterisation of different proteins, using the powerful information provided by Structural Biology methods. The atomic level information obtained allows drawing conclusions related to macromolecular interactions.
  • Study of the phenomena behind protein crystallization and new methods to improve it.


  • PhD in Structural Biology, Universidade Nova de Lisboa (2002)
  • MSc in Biophysics, Faculdade de Ciências da Universidade de Lisboa (1997)
  • Graduation in Applied Chemistry, FCT-NOVA (1995)