Ana Luísa Carvalho

Independent Researcher

Assistant Investigator (since 2003)
Personal Website
Phone number
+351212948300 (ext: 10940)
Researcher ID
Ciência Vitae

Main publications

  • Carvalho, Ana Luísa, Teresa Santos-Silva, Maria João Romão, J. Eurico, and Filipa Marcelo. 2018. CHAPTER 2 Structural Elucidation of Macromolecules. Essential Techniques for Medical and Life Scientists: A Guide to Contemporary Methods and Current Applications with the Protocols, DOI: 10.2174/9781681087092118010005
  • Gomes, Ana Sara, Filipa Trovão, Benedita Andrade Pinheiro, Filipe Freire, Sara Gomes, Carla Oliveira, Lucília Domingues, Maria João Romão, Lucília Saraiva, and Ana Luísa Carvalho. 2018. The Crystal Structure of the R280K Mutant of Human p53 Explains the Loss of DNA Binding. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 19(1184), DOI: 10.3390/ijms19041184
  • Pedro Bule; Virgínia MRPires; Victor DAlves; Ana Luísa Carvalho; José AMPrates; Luís MAFerreira; Steven PSmith; Harry JGilbert; Ilit Noach; Edward ABayer; Shabir Najmudin; Carlos MGAFontes. 2018. Higher order scaffoldin assembly in Ruminococcus flavefaciens cellulosome is coordinated by a discrete cohesin-dockerin interaction. Scientific Reports, 8(6987), DOI: 10.1038/s41598-018-25171-8
  • Kryshtafovych, A; Albrecht, R; Basle, A; Bule, P; Caputo, AT; Carvalho, AL; Chao, KL; Diskin, R; Fidelis, K; Fontes, CMGA; Fredslund, F; Gilbert, HJ; Goulding, CW; Hartmann, MD; Hayes, CS; Herzberg, O; Hill, JC; Joachimiak, A; Kohring, GW; Koning, RI; Lo Leggio, L; Mangiagalli, M; Michalska, K; Moult, J; Najmudin, S; Nardini, M; Nardone, V; Ndeh, D; Nguyen, TH; Pintacuda, G; Postel, S; van Raaij, MJ; Roversi, P; Shimon, A; Singh, AK; Sundberg, EJ; Tars, K; Zitzmann, N; Schwede, T. 2018. Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016). PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 86, DOI: 10.1002/prot.25392
  • Peixoto, D; Figueiredo, M; Malta, G; Roma-Rodrigues, C; Baptista, PV; Fernandes, AR; Barroso, S; Carvalho, AL; Afonso, CAM; Ferreira, LM; Branco, PS. 2018. Synthesis, Cytotoxicity Evaluation in Human Cell Lines and in Vitro DNA Interaction of a Hetero-Arylidene-9(10H)-Anthrone. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, DOI: 10.1002/ejoc.201701500

Main research interests

  • Functional and structural characterisation of different proteins, using the powerful information provided by Structural Biology methods. The atomic level information obtained allows drawing conclusions related to macromolecular interactions.
  • Study of the phenomena behind protein crystallization and new methods to improve it.


  • PhD in Structural Biology, Universidade Nova de Lisboa (2002)
  • MSc in Biophysics, Faculdade de Ciências da Universidade de Lisboa (1997)
  • Graduation in Applied Chemistry, FCT-NOVA (1995)