People

Ana Rita Grosso

Research Lab Leader

Position
Assistant Investigator (since 2018)
Email
argrosso@fct.unl.pt
Researcher ID

Main publications

  • Mafalda Ramos de Matos; Ioana Posa; Filipa Sofia Carvalho; Vanessa Alexandra Morais; Ana Rita Grosso; Sérgio Fernandes de Almeida. 2019. A Systematic Pan-Cancer Analysis of Genetic Heterogeneity Reveals Associations with Epigenetic Modifiers. Cancers, DOI: 10.3390/cancers11030391
  • Alexandra CVítor; Sreerama CSridhara; João CSabino; Ana IAfonso; Ana RGrosso; Robert MMartin; Sérgio Fde Almeida. 2019. Single-molecule imaging of transcription at damaged chromatin. Science Advances, 5(1), DOI: 10.1126/sciadv.aau1249
  • Nojima, Takayuki; Rebelo, Kenny; Gomes, Tomas; Grosso, Ana Rita; Proudfoot, Nicholas J; Carmo-Fonseca, Maria. 2018. RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing. MOLECULAR CELL, 72(2), DOI: 10.1016/j.molcel.2018.09.004
  • Bonnet A, Grosso AR, Elkaoutari A, Coleno E, Presle A, Sridhara SC, Janbon G, Géli V, de Almeida SF, Palancade B.. 2017. Introns Protect Eukaryotic Genomes from Transcription-Associated Genetic Instability.. MOLECULAR CELL, 67(4), DOI: 10.1016/j.molcel.2017.07.002
  • Posa, I; Carvalho, S; Tavares, J; Grosso, AR. 2016. A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma. Oncotarget, 7(30), DOI: 10.18632/oncotarget.9487
  • Nojima T, Gomes T, Grosso ARF, Kimura H, Dye MJ, Dhir S, Carmo-Fonseca M, Proudfoot NJ.. 2015. Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing. CELL, 161(3), DOI: 10.1016/j.cell.2015.03.027
  • Grosso, AR; Leite, AP; Carvalho, S; Matos, MR; Martins, FB; Vítor, AC; Desterro, JMP; Carmo-Fonseca, M; de Almeida, SF. 2015. Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma. eLife, 4(NOVEMBER2015), DOI: 10.7554/eLife.09214

Main research interests

  • Computational Biology & Bioinformatics
  • Decipher diseases using multi-omics approaches
  • Genome and Epigenetic Alterations

Degrees

  • Graduation in Biology, Faculdade de Ciências da Universidade de Lisboa (2002)
  • MSc in Bioinformatics, Faculdade de Ciências da Universidade de Lisboa (2006)
  • PhD in Ciências Biomédicas, Faculdade de Medicina da Universidade de Lisboa (2010)