People

Cristiano Mota

Researcher

Position
DL 57 contract (since 2018)
Email
cd.mota@fct.unl.pt
Phone number
+351212948300 (ext: 10962)
Researcher ID

Main publications

  • Cristiano Mota; Mariam Esmaeeli; Catarina Coelho; Teresa Santos‐Silva; Martin Wolff; Alessandro Foti; Silke Leimkühler; Maria João Romão. 2019. Human aldehyde oxidase ( hAOX 1): structure determination of the Moco‐free form of the natural variant G1269R and biophysical studies of single nucleotide polymorphisms. FEBS Open Bio, DOI: 10.1002/2211-5463.12617
  • Mota, C; Coelho, C; Leimkuhler, S; Garattini, E; Terao, M; Santos-Silva, T; Romao, MJ. 2018. Critical overview on the structure and metabolism of human aldehyde oxidase and its role in pharmacokinetics. COORDINATION CHEMISTRY REVIEWS, 368, DOI: 10.1016/j.ccr.2018.04.006
  • Le Marchand, Tanguy; de Rosa, Matteo; Salvi, Nicola; Sala, Benedetta Maria; Andreas, Loren B; Barbet-Massin, Emeline; Sormanni, Pietro; Barbiroli, Alberto; Porcari, Riccardo; Sousa Mota, Cristiano; de Sanctis, Daniele; Bolognesi, Martino; Emsley, Lyndon; Bellotti, Vittorio; Blackledge, Martin; Camilloni, Carlo; Pintacuda, Guido; Ricagno, Stefano. 2018. Conformational dynamics in crystals reveal the molecular bases for D76N beta-2 microglobulin aggregation propensity.. Nature Communications, 9(1), DOI: 10.1038/s41467-018-04078-y
  • Mota, Cristiano S; Goncalves, Ana Maria D; de Sanctis, Daniele. 2016. Deinococcus radiodurans DR2231 is a two-metal-ion mechanism hydrolase with exclusive activity on dUTP. FEBS Journal, 283(23), DOI: 10.1111/febs.13923
  • Gonzalez, PJ; Rivas, MG; Mota, CS; Brondino, CD; Moura, I; Moura, JJG. 2013. Periplasmic nitrate reductases and formate dehydrogenases: Biological control of the chemical properties of Mo and W for fine tuning of reactivity, substrate specificity and metabolic role. COORDINATION CHEMISTRY REVIEWS, 257, DOI: 10.1016/j.ccr.2012.05.020
  • Mota, CS; Valette, O; Gonzalez, PJ; Brondino, CD; Moura, JJG; Moura, I; Dolla, A; Rivas, MG. 2011. Effects of Molybdate and Tungstate on Expression Levels and Biochemical Characteristics of Formate Dehydrogenases Produced by Desulfovibrio alaskensis NCIMB 13491. JOURNAL OF BACTERIOLOGY, 193, DOI: 10.1128/JB.01531-10
  • Mota, CS; Rivas, MG; Brondino, CD; Moura, I; Moura, JJG; Gonzalez, PJ; Cerqueira, NMFSA. 2011. The mechanism of formate oxidation by metal-dependent formate dehydrogenases. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 16, DOI: 10.1007/s00775-011-0813-8
  • Rivas, MG; Mota, CS; Pauleta, SR; Carepo, MSP; Folgosa, F; Andrade, SLA; Fauque, G; Pereira, AS; Tavares, P; Calvete, JJ; Moura, I; Moura, JJG. 2009. Isolation and characterization of a new Cu-Fe protein from Desulfovibrio aminophilus DSM12254. JOURNAL OF INORGANIC BIOCHEMISTRY, 103, DOI: 10.1016/j.jinorgbio.2009.04.014
  • Rivas, MG; Carepo, MSP; Mota, CS; Korbas, M; Durand, MC; Lopes, AT; Brondino, CD; Pereira, AS; George, GN; Dolla, A; Moura, JJG; Moura, I. 2009. Molybdenum Induces the Expression of a Protein Containing a New Heterometallic Mo-Fe Cluster in Desulfovibrio alaskensis. BIOCHEMISTRY, 48, DOI: 10.1021/65801773t
  • Santos, HM; Mota, C; Lodeiro, C; Moura, I; Isaac, I; Capelo, JL. 2008. An improved clean sonoreactor-based method for protein identification by mass spectrometry-based techniques. TALANTA, 77, DOI: 10.1016/j.talanta.2008.07.048

Main research interests

  • Metalloenzymes and Enzymatic Mechanisms

Degrees

  • Graduation in Biochemistry, Faculdade de Ciências - Universidade Nova de Lisboa (2006)
  • PhD in Biochemistry, Faculdade de Ciências e Tecnologia - Universidade Nova de Lisboa (2011)