People

Filipa Marcelo

Independent Researcher

Position
Assistant Investigator (since 2016)
Email
filipa.marcelo@fct.unl
Phone number
212948300 (ext: 11401)
Researcher ID
Ciência Vitae

Main publications

  • de las Rivas, Matilde; Paul Daniel, Earnest James; Narimatsu, Yoshiki; Compañón, Ismael; Kato, Kentaro; Hermosilla, Pablo; Thureau, Aurélien; et al. 2020. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nature Chemical Biology, 16(3), DOI: 10.1038/s41589-019-0444-x
  • Gomes, AS; Ramos, H; Gomes, S; Loureiro, JB; Soares, J; Barcherini, V; Monti, P; Fronza, G; Oliveira, C; Domingues, L; Bastos, M; Dourado, DFAR; Carvalho, AL; Romão, MJ; Pinheiro, B; Marcelo, F; Carvalho, A; Santos, MMM; Saraiva, L. 2020. SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1864(1), DOI: 10.1016/j.bbagen.2019.129440
  • Ana Diniz; Helena Coelho; Jorge SDias; Sandra JVliet; Jesús Jiménez‐Barbero; Francisco Corzana; Eurico JCabrita; Filipa Marcelo. 2019. The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose‐Type Lectin. Chemistry – A European Journal, 25(61), DOI: 10.1002/chem.201902780
  • Marcelo, F; Supekar, N; Corzana, F; van der Horst, JC; Vuist, IM; Live, D; Boons, GJPH; Smith, DF; van Vliet, SJ. 2019. Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands. JOURNAL OF BIOLOGICAL CHEMISTRY, 294, DOI: 10.1074/jbc.RA118.004957
  • Siopa, F; Frade, RFM; Diniz, A; Andrade, JM; Nicolai, M; Meirinhos, A; Lucas, SD; Marcelo, F; Afonso, CAM; Rijo, P. 2018. Acetylcholinesterase Choline-Based Ionic Liquid Inhibitors: In Vitro and in Silico Molecular Docking Studies. ACS OMEGA, 3, DOI: 10.1021/acsomega.8b02347

Main research interests

  • Glycosciences
  • Molecular Recognition
  • NMR
  • Glycosylation

Degrees

  • PhD in Organic Chemistry, Universidade de Lisboa and Université Pierre et Marie Curie Paris VI (2009)
  • Graduation in Chemistry, Faculdade de Ciências da Universidade de Lisboa (2003)