People

Filipa Marcelo

Independent Researcher

Position
Assistant Investigator (since 2016)
Email
filipa.marcelo@fct.unl
Phone number
212948300 (ext: 11401)
Researcher ID
Ciência Vitae

Recent publications

  • de Matos, AM; Blazquez-Sanchez, MT; Bento-Oliveira, A; de Almeida, RFM; Nunes, R; Lopes, PEM; Machuqueiro, M; Cristovao, JS; Gomes, CM; Souza, CS; El Idrissi, IG; Colabufo, NA; Diniz, A; Marcelo, F; Oliveira, MC; Lopez, O; Fernandez-Bolanos, JG; Datwyler, P; Ernst, B; Ning, K; Garwood, C; Chen, BN; Rauter, AP. 2020. Glucosylpolyphenols as Inhibitors of A beta-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease. JOURNAL OF MEDICINAL CHEMISTRY, 63, DOI: 10.1021/acs.jmedchem.0c00841
  • Macias-Leon, J; Bermejo, IA; Asin, A; Garcia-Garcia, A; Companon, I; Jimenez-Moreno, E; Coelho, H; Mangini, V; Albuquerque, IS; Marcelo, F; Asensio, JL; Bernardes, GJL; Joshi, HJ; Fiammengo, R; Blixt, O; Hurtado-Guerrero, R; Corzana, F. 2020. Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody. CHEMICAL COMMUNICATIONS, 56, DOI: 10.1039/d0cc06349e
  • Lenza, MP; Oyenarte, I; Diercks, T; Quintana, JI; Gimeno, A; Coelho, H; Diniz, A; Peccati, F; Delgado, S; Bosch, A; Valle, M; Millet, O; Abrescia, NGA; Palazon, A; Marcelo, F; Jimenez-Oses, G; Jimenez-Barbero, J; Arda, A; Ereno-Orbea, J. 2020. Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, DOI: 10.1002/anie.202011015
  • de las Rivas, Matilde; Paul Daniel, Earnest James; Narimatsu, Yoshiki; Compañón, Ismael; Kato, Kentaro; Hermosilla, Pablo; Thureau, Aurélien; et al. 2020. Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3. Nature Chemical Biology, 16(3), DOI: 10.1038/s41589-019-0444-x
  • Gomes, AS; Ramos, H; Gomes, S; Loureiro, JB; Soares, J; Barcherini, V; Monti, P; Fronza, G; Oliveira, C; Domingues, L; Bastos, M; Dourado, DFAR; Carvalho, AL; Romão, MJ; Pinheiro, B; Marcelo, F; Carvalho, A; Santos, MMM; Saraiva, L. 2020. SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1864(1), DOI: 10.1016/j.bbagen.2019.129440

Main research interests

  • Glycosciences
  • Molecular Recognition
  • NMR
  • Glycosylation

Degrees

  • PhD in Organic Chemistry, Universidade de Lisboa and Université Pierre et Marie Curie Paris VI (2009)
  • Graduation in Chemistry, Faculdade de Ciências da Universidade de Lisboa (2003)