People

Helena Coelho

Researcher

Position
Junior Investigator (since 2019)
Email
h.coelho@campus.fct.unl.pt
Phone number
212948300 (ext: 10954)
Researcher ID

Main publications

  • Florent Cochet, Fabio A. Facchini, Lenny Zaffaroni, Jean-Marc Billod, Helena Coelho, Aurora Holgado, Harald Braun, Rudi Beyaert, Roman Jerala, Jesus Jimenez-Barbero, Sonsoles Martin-Santamaria & Francesco Peri. 2019. Novel carboxylate-based glycolipids: TLR4 antagonism, MD-2 binding and self-assembly properties. Scientific Reports, DOI: 10.1038/s41598-018-37421-w
  • de las Rivas, M; Daniel, EJP; Coelho, H; Lira-Navarrete, E; Raich, L; Companon, I; Diniz, A; Lagartera, L; Jimenez-Barbero, J; Clausen, H; Rovira, C; Marcelo, F; Corzana, F; Gerken, TA; Hurtado-Guerrero, R. 2018. Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4. ACS Central Science, 4, DOI: 10.1021/acscentsci.8b00488
  • Matilde de las Rivas, Helena Coelho, Ana Diniz, Erandi Lira-Navarrete, Ismael Compañón, Jesús Jiménez-Barbero, Katrine T. Schjoldager, Eric P. Bennett, Sergey Y. Vakhrushev, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero. 2018. Structural analysis of a GalNAc‐T2 mutant reveals an induced‐fit catalytic mechanism for GalNAc‐Ts. Chemistry – A European Journal, 24, DOI: 10.1002/chem.201800701
  • Facchini, FA; Coelho, H; Sestito, SE; Delgado, S; Minotti, A; Andreu, D; Jimenez-Barbero, J; Peri, F. 2018. Co-administration of Antimicrobial Peptides Enhances Toll-like Receptor4 Antagonist Activity of a Synthetic Glycolipid. ChemMedChem, 13, DOI: 10.1002/cmdc.201700694

Degrees

  • Bachelor in Biochemistry, Universidade NOVA de Lisboa, Faculdade de Ciências e Tecnologia (2011)
  • MSc in Biotechnology, Universidade NOVA de Lisboa, Faculdade de Ciências e Tecnologia (2013)
  • PhD in Biochemistry / Synthetic and Industrial Chemistry, Universidade NOVA de Lisboa and Universidad del País Vasco, Bilbao, Spain (2019)