People

Helena Coelho

Researcher

Position
Junior Investigator (since 2019)
Email
h.coelho@campus.fct.unl.pt
Phone number
212948300 (ext: 10954)
Researcher ID

Main publications

  • de las Rivas, M; Daniel, EJP; Coelho, H; Lira-Navarrete, E; Raich, L; Companon, I; Diniz, A; Lagartera, L; Jimenez-Barbero, J; Clausen, H; Rovira, C; Marcelo, F; Corzana, F; Gerken, TA; Hurtado-Guerrero, R. 2018. Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4. ACS Central Science, 4, DOI: 10.1021/acscentsci.8b00488
  • Matilde de las Rivas, Helena Coelho, Ana Diniz, Erandi Lira-Navarrete, Ismael Compañón, Jesús Jiménez-Barbero, Katrine T. Schjoldager, Eric P. Bennett, Sergey Y. Vakhrushev, Henrik Clausen, Francisco Corzana, Filipa Marcelo, Ramon Hurtado-Guerrero. 2018. Structural analysis of a GalNAc‐T2 mutant reveals an induced‐fit catalytic mechanism for GalNAc‐Ts. Chemistry – A European Journal, 24, DOI: 10.1002/chem.201800701
  • de las Rivas, M; Lira-Navarrete, E; Daniel, EJP; Companon, I; Coelho, H; Diniz, A; Jimenez-Barbero, J; Peregrina, JM; Clausen, H; Corzana, F; Marcelo, F; Jimenez-Oses, G; Gerken, TA; Hurtado-Guerrero, R. 2017. The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences. Nature Communications, 8, DOI: 10.1038/s41467-017-02006-0
  • Coelho, H; Matsushita, T; Artigas, G; Hinou, H; Canada, FJ; Lo-Man, R; Leclerc, C; Cabrita, EJ; Jimenez-Barbero, J; Nishimura, S; Garcia-Martin, F; Marcelo, F. 2015. The Quest for Anticancer Vaccines: Deciphering the Fine-Epitope Specificity of Cancer-Related Monoclonal Antibodies by Combining Microarray Screening and Saturation Transfer Difference NMR. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 137, DOI: 10.1021/jacs.5b06787

Degrees

  • Bachelor in Biochemistry, Universidade NOVA de Lisboa, Faculdade de Ciências e Tecnologia (2011)
  • MSc in Biotechnology, Universidade NOVA de Lisboa, Faculdade de Ciências e Tecnologia (2013)
  • PhD in Biochemistry / Synthetic and Industrial Chemistry, Universidade NOVA de Lisboa and Universidad del País Vasco, Bilbao, Spain (2019)