People

Margarida Borges

Independent Researcher

Position
Assistant Professor (since 2010)
Personal Website
Email
mborges@ff.up.pt
Phone number
(+351) 22 0420 8500 (ext: 8565)
Researcher ID

Main publications

  • Resende, M; Cardoso, MS; Ribeiro, AR; Florido, M; Borges, M; Castro, AG; Alves, NL; Cooper, AM; Appelberg, R. 2017. Innate IFN-gamma-Producing Cells Developing in the Absence of IL-2 Receptor Common gamma-Chain. JOURNAL OF IMMUNOLOGY, 199, DOI: 10.4049/jimmunol.1601701
  • Vieira, Alexandre Cc; Magalhaes, Joana; Rocha, Sonia; Cardoso, Marcos S; Santos, Susana G; Borges, Margarida; Pinheiro, Marina; Reis, Salette. 2017. Targeted macrophages delivery of rifampicin-loaded lipid nanoparticles to improve tuberculosis treatment.. Nanomedicine (London, England), 12(24), DOI: 10.2217/nnm-2017-0248
  • Brito, C; Goncalves, A; Silva, TM; Teixeira, N; Borges, M. 2016. Determination of macrophage activation profile during Toxoplasma gondii infection and implications on pregnancy outcome using the mice model. MEDICINE, 95, DOI:
  • Cardoso, MS; Silva, TM; Resende, M; Appelberg, R; Borges, M. 2015. Lack of the Transcription Factor Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) in Macrophages Accelerates the Necrosis of Mycobacterium avium-Induced Granulomas. INFECTION AND IMMUNITY, 83, DOI: 10.1128/IAI.00144-15
  • Borges, M; Barreira-Silva, P; Flórido, M; Jordan, MB; Correia-Neves, M; Appelberg, R. 2012. Molecular and cellular mechanisms of Mycobacterium avium-induced thymic atrophy. JOURNAL OF IMMUNOLOGY, 189(7), DOI: 10.4049/jimmunol.1201525
  • Borges, M; Rosa, GT; Appelberg, R. 2011. The death-promoting molecule tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 164(3), DOI: 10.1111/j.1365-2249.2011.04385.x
  • Flórido, M; Pearl, JE; Solache, A; Borges, M; Haynes, L; Cooper, AM; Appelberg, R. 2005. Gamma interferon-induced T-cell loss in virulent Mycobacterium avium infection. INFECTION AND IMMUNITY, 73(6), DOI: 10.1128/IAI.73.6.3577-3586.2005
  • Borges, M; Da Silva, AC; Sereno, D; Ouaissi, A. 2003. Peptide-based analysis of the amino acid sequence important to the immunoregulatory function of Trypanosoma cruzi Tc52 virulence factor. IMMUNOLOGY, 109(1), DOI: 10.1046/j.1365-2567.2003.01637.x

Main research interests

  • Immunopathology of Infection
  • In vitro models of parasite and bacterial infection
  • In vivo model of T. gondii vertical transmission
  • Screening of anti-parasitic and anti-bacterial agents
  • Search of vaccines avoiding parasite replication and invasion

Degrees

  • PhD in Bioquímica, Faculty of Pharmacy University of Porto (2003)
  • Graduation in Pharmaceutical Sciences, Faculty of Pharmacy, University of Porto (1998)