Margarida Borges

Independent Researcher

Assistant Professor (since 2010)
Personal Website
Phone number
(+351) 22 0420 8500 (ext: 8565)
Researcher ID

Main publications

  • Carina Brito; Tânia MSilva; Maria MCastro; Weronika Wyrwas; Bárbara Oliveira; Bruno MFonseca; Pedro Oliveira; Craig WRoberts; Natércia Teixeira; Margarida Borges. 2020. Toxoplasma gondii infection reduces serum progesterone levels and adverse effects at the maternal‐foetal interface. PARASITE IMMUNOLOGY, DOI: 10.1111/pim.12690
  • Vieira, Alexandre Cc; Magalhaes, Joana; Rocha, Sonia; Cardoso, Marcos S; Santos, Susana G; Borges, Margarida; Pinheiro, Marina; Reis, Salette. 2017. Targeted macrophages delivery of rifampicin-loaded lipid nanoparticles to improve tuberculosis treatment.. Nanomedicine (London, England), 12(24), DOI: 10.2217/nnm-2017-0248
  • Brito, C; Goncalves, A; Silva, TM; Teixeira, N; Borges, M. 2016. Determination of macrophage activation profile during Toxoplasma gondii infection and implications on pregnancy outcome using the mice model. MEDICINE, 95, DOI:
  • Cardoso, MS; Silva, TM; Resende, M; Appelberg, R; Borges, M. 2015. Lack of the Transcription Factor Hypoxia-Inducible Factor 1 alpha (HIF-1 alpha) in Macrophages Accelerates the Necrosis of Mycobacterium avium-Induced Granulomas. INFECTION AND IMMUNITY, 83, DOI: 10.1128/IAI.00144-15
  • Borges, M; Rosa, GT; Appelberg, R. 2011. The death-promoting molecule tumour necrosis factor-related apoptosis inducing ligand (TRAIL) is not required for the development of peripheral lymphopenia or granuloma necrosis during infection with virulent Mycobacterium avium. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 164(3), DOI: 10.1111/j.1365-2249.2011.04385.x
  • Borges, M; Da Silva, AC; Sereno, D; Ouaissi, A. 2003. Peptide-based analysis of the amino acid sequence important to the immunoregulatory function of Trypanosoma cruzi Tc52 virulence factor. IMMUNOLOGY, 109(1), DOI: 10.1046/j.1365-2567.2003.01637.x

Main research interests

  • Immunopathology of Infection
  • In vitro models of parasite and bacterial infection
  • In vivo model of T. gondii vertical transmission
  • Screening of anti-parasitic and anti-bacterial agents
  • Search of vaccines avoiding parasite replication and invasion


  • PhD in Biochemistry, Faculty of Pharmacy University of Porto (2003)
  • Graduation in Pharmaceutical Sciences, Faculty of Pharmacy, University of Porto (1998)