Maria João Ramos

Research Group Coordinator

Full Professor (since 2009)
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Main publications

  • Ramos, MJ; Fernandes, PA. 2008. Computational enzymatic catalysis. ACCOUNTS OF CHEMICAL RESEARCH, 41, DOI: 10.1021/ar7001045
  • Sousa, SF; Fernandes, PA; Ramos, MJ. 2008. Farnesyltransferase inhibitors: A detailed chemical view on an elusive biological problem. CURRENT MEDICINAL CHEMISTRY, 15, DOI: 10.2174/092986708784638825
  • da Fonseca, RR; Johnson, WE; O'Brien, SJ; Ramos, MJ; Antunes, A. 2008. The adaptive evolution of the mammalian mitochondrial genome. BMC GENOMICS, 9, DOI: 10.1186/1471-2164-9-119
  • Moreira, IS; Fernandes, PA; Ramos, MJ. 2007. Computational alanine scanning mutagenesis - An improved methodological approach. JOURNAL OF COMPUTATIONAL CHEMISTRY, 28, DOI: 10.1002/jcc.20566
  • Sousa, SF; Fernandes, PA; Ramos, MJ. 2007. The carboxylate shift in zinc enzymes: A computational study. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 129, DOI: 10.1021/ja067103n
  • Moreira, IS; Fernandes, PA; Ramos, MJ. 2007. Hot spots-A review of the protein-protein interface determinant amino-acid residues. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 68, DOI: 10.1002/prot.21396
  • Sousa, SF; Fernandes, PA; Ramos, MJ. 2007. General performance of density functionals. JOURNAL OF PHYSICAL CHEMISTRY A, 111, DOI: 10.1021/jp0734474
  • Sousa, SF; Fernandes, PA; Ramos, MJ. 2006. Protein-ligand docking: Current status and future challenges. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 65, DOI: 10.1002/prot.21082
  • Pande, V; Ramos, MJ. 2005. NF-kappa B in human disease: current inhibitors and prospects for de novo structure based design of inhibitors. CURRENT MEDICINAL CHEMISTRY, 12, DOI: 10.2174/0929867053363180
  • Fernandes, PA; Ramos, MJ. 2004. Theoretical insights into the mechanism for thiol/disulfide exchange. CHEMISTRY-A EUROPEAN JOURNAL, 10, DOI: 10.1002/chem.200305343

Main research interests

  • Enzyme Catalysis
  • Molecular Dynamics of Proteins
  • Computational Mutagenesis
  • Software Development
  • Drug Discovery