Maria João Romão

Research Group Coordinator

Full Professor (since 2012)
Personal Website
Phone number
(+351) 212948310 (ext: 10963/2)
Researcher ID
Ciência Vitae

Main publications

  • Oliveira, AR; Mota, C; Mourato, C; Domingos, RM; Santos, MFA; Gesto, D; Guigliarelli, B; Santos-Silva, T; Romao, MJ; Pereira, IAC. 2020. Toward the Mechanistic Understanding of Enzymatic CO2 Reduction. ACS Catalysis, 10, DOI: 10.1021/acscatal.0c00086
  • Terao, M; Garattini, E; Romao, MJ; Leimkuhler, S. 2020. Evolution, expression, and substrate specificities of aldehyde oxidase enzymes in eukaryotes. JOURNAL OF BIOLOGICAL CHEMISTRY, 295, DOI: 10.1074/jbc.REV119.007741
  • Ferreira, P; Cerqueira, NMFSA; Coelho, C; Fernandes, PA; Romao, MJ; Ramos, MJ. 2019. New insights about the monomer and homodimer structures of the human AOX1. PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 21, DOI: 10.1039/c9cp01040h
  • Cristiano Mota; Teresa Santos-Silva; Mineko Terao; Enrico Garattini; Maria João Romão; Silke Leimkühler. 2019. Aldehyde Oxidases as Enzymes in Phase I Drug Metabolism. Pharmaceutical Biocatalysis, DOI: 10.1201/9780429295034-13
  • Cristiano Mota; Mariam Esmaeeli; Catarina Coelho; Teresa Santos‐Silva; Martin Wolff; Alessandro Foti; Silke Leimkühler; Maria João Romão. 2019. Human aldehyde oxidase ( hAOX 1): structure determination of the Moco‐free form of the natural variant G1269R and biophysical studies of single nucleotide polymorphisms. FEBS Open Bio, DOI: 10.1002/2211-5463.12617

Main research interests

  • Novel methods for protein crystallization
  • Metalloenzymes and Enzymatic Mechanisms
  • Molybdoenzymes
  • Aldehyde Oxidase and Drug Metabolism
  • Cellulosomal enzymes


  • "Agregação" in Biochemistry, Faculdade de Ciências e Tecnologia, Universidade NOVA de Lisboa (2001)
  • PhD in Chemistry, Instituto Superior Técnico, ULisboa (1989)