People

Sofia Pauleta

Research Lab Leader

Position
Principal Investigator (since 2014)
Email
srp@fct.unl.pt
Phone number
(+351) 212948300 (ext: 10967)
Researcher ID

Main publications

  • Nobrega, CS; Devreese, B; Pauleta, SR. 2018. YhjA - An Escherichia coli trihemic enzyme with quinol peroxidase activity. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1859, DOI: 10.1016/j.bbabio.2018.03.008
  • Nobrega, CS; Raposo, M; Van Driessche, G; Devreese, B; Pauleta, SR. 2017. Biochemical characterization of the bacterial peroxidase from the human pathogen Neisseria gonorrhoeae. JOURNAL OF INORGANIC BIOCHEMISTRY, 171, DOI: 10.1016/j.jinorgbio.2017.03.007
  • Johnston, EM; Carreira, C; Dell'Acqua, S; Dey, SG; Pauleta, SR; Moura, I; Solomon, EI. 2017. Spectroscopic Definition of the Cu-Z degrees Intermediate in Turnover of Nitrous Oxide Reductase and Molecular Insight into the Catalytic Mechanism. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 139, DOI: 10.1021/jacs.6b13225
  • Maiti, BK; Maia, LB; Pauleta, SR; Moura, I; Moura, JJG. 2017. Protein-Assisted Formation of Molybdenum Heterometallic Clusters: Evidence for the Formation of S2MoS2-M-S2MoS2 Clusters with M = Fe, Co, Ni, Cu, or Cd within the Orange Protein. INORGANIC CHEMISTRY, 56, DOI: 10.1021/acs.inorgchem.6b02906
  • Nobrega, CS; Saraiva, IH; Carreira, C; Devreese, B; Matzapetakis, M; Pauleta, SR. 2016. The solution structure of the soluble form of the lipid-modified azurin from Neisseria gonorrhoeae, the electron donor of cytochrome c peroxidase. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1857, DOI: 10.1016/j.bbabio.2015.11.006
  • Maiti, BK; Moura, I; Moura, JJG; Pauleta, SR. 2016. The small iron-sulfur protein from the ORP operon binds a [2Fe-2S] cluster. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, 1857, DOI: 10.1016/j.bbabio.2016.05.006
  • Almeida, RM; Dell'Acqua, S; Krippahl, L; Moura, JJG; Pauleta, SR. 2016. Predicting Protein-Protein Interactions Using BiGGER: Case Studies. MOLECULES, 21, DOI: 10.3390/molecules21081037
  • Neca, AJ; Soares, R; Carepo, MSP; Pauleta, SR. 2016. Resonance assignment of DVU2108 that is part of the Orange Protein complex in Desulfovibrio vulgaris Hildenborough. Biomolecular NMR Assignments, 10, DOI: 10.1007/s12104-015-9648-5
  • Carepo, MSP; Carreira, C; Grazina, R; Zakrzewska, ME; Dolla, A; Aubert, C; Pauleta, SR; Moura, JJG; Moura, I. 2016. Orange protein from Desulfovibrio alaskensis G20: insights into the Mo-Cu cluster protein-assisted synthesis. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 21, DOI: 10.1007/s00775-015-1323-x
  • Maiti, BK; Maia, LB; Silveira, CM; Todorovic, S; Carreira, C; Carepo, MSP; Grazina, R; Moura, I; Pauleta, SR; Moura, JJG. 2015. Incorporation of molybdenum in rubredoxin: models for mononuclear molybdenum enzymes. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY, 20, DOI: 10.1007/s00775-015-1268-0
  • Johnston, EM; Dell'Acqua, S; Pauleta, SR; Moura, I; Solomon, EI. 2015. Protonation state of the Cu4S2 Cu-Z site in nitrous oxide reductase: redox dependence and insight into reactivity. Chemical Science, 6, DOI: 10.1039/c5sc02102b

Main research interests

  • Reactive oxygen species; Metalloenzymes; Bacterial Peroxidase; Copper Stress; Denitrification; Structural Biology - NMR

Degrees

  • PhD in Biochemistry-Biophysical Chemistry, Universidade Nova de Lisboa (2003)
  • Graduation in Química Aplicada - biotecnologia, Faculdade de ciências e Tecnologia (1998)