Susana P. Gaudêncio

Research Lab Leader

Research Group
Assistant Investigator (since 2012)
Personal Website
Phone number
(+351) 212948300 (ext: 10994)
Researcher ID

Main publications

  • Bauermeister, Anelize; Pereira, Florbela; Grilo, Ines R; Godinho, Camila C; Paulino, Marisa; Almeida, Vanessa; Gobbo-Neto, Leonardo; Prieto-Davo, Alejandra; Sobral, Rita G; Lopes, Norberto P; Gaudencio, Susana P. 2019. Intra-clade metabolomic profiling of MAR4 Streptomyces from the Macaronesia Atlantic region reveals a source of anti-biofilm metabolites.. ENVIRONMENTAL MICROBIOLOGY, DOI: 10.1111/1462-2920.14529
  • Cruz, S; Gomes, SE; Borralho, PM; Rodrigues, CMP; Gaudencio, SP; Pereira, F. 2018. In Silico HCT116 Human Colon Cancer Cell-Based Models En Route to the Discovery of Lead-Like Anticancer Drugs. BIOMOLECULES, 8, DOI: 10.3390/biom8030056
  • Bauermeister, A; Velasco-Alzate, K; Dias, T; Macedo, H; Ferreira, EG; Jimenez, PC; Lotufo, TMC; Lopes, NP; Gaudencio, SP; Costa-Lotufo, LV. 2018. Metabolomic Fingerprinting of Salinispora From Atlantic Oceanic Islands. Frontiers in Microbiology, 9, DOI: 10.3389/fmicb.2018.03021
  • Bauermeister Anelize, Pereira Florbela, Grilo Inês, Prieto-Davo Alejandra, Sobral Rita G, Lopes Norberto P, Gaudêncio Susana P. 2018. Molecular Networking to target the isolation of novel isoprenoids derivatives from marine-derived actinomycetes. Frontiers in Marine Science, DOI: 10.3389/conf.fmars.2018.06.00160
  • Dias, Tiago; Gaudencio, Susana P; Pereira, Florbela. 2018. A Computer-Driven Approach to Discover Natural Product Leads for Methicillin-Resistant Staphylococcus aureus Infection Therapy.. Marine Drugs, 17(1), DOI: 10.3390/md17010016
  • Letzel, AC; Li, J; Amos, GCA; Millan-Aguinaga, N; Ginigini, J; Abdelmohsen, UR; Gaudencio, SP; Ziemert, N; Moore, BS; Jensen, PR. 2017. Genomic insights into specialized metabolism in the marine actinomycete Salinispora. ENVIRONMENTAL MICROBIOLOGY, 19, DOI: 10.1111/1462-2920.13867
  • Fernandes Ana F, Costa Ligia, Santos-Sanches Ilda, Gaudêncio Susana P, Almeida M Gabriela. 2016. Identification of the Streptomyces aculeolatus proteins involved in the biosynthesis of bioactive compound by a comparative 2D electrophoresis approach. Frontiers in Marine Science, DOI: 10.3389/conf.FMARS.2016.04.00057
  • Sousa Joana Rita, Dias Tiago Rodrigues Sara Santos-Sanches Ilda Gaudêncio Susana PAlmeida MGabriela. 2016. Identification of protein markers for bioactivity in marine actinomycetes: a proteomic analysis. Frontiers in Marine Science, DOI: 10.3389/conf.FMARS.2016.04.00063
  • Cruz, Sara Mamede; Gaudêncio, Susana; Pereira, Florbela. 2016. A computational approach for the discovery of lead-like compounds for anticancer drugs. Frontiers in Marine Science, DOI: 10.3389/conf.FMARS.2016.04.00122
  • Roca, C; Lehmann, M; Torres, CAV; Baptista, S; Gaudencio, SP; Freitas, F; Reis, MAM. 2016. Exopolysaccharide production by a marine Pseudoalteromonas sp strain isolated from Madeira Archipelago ocean sediments. New Biotechnology, 33, DOI: 10.1016/j.nbt.2016.02.005
  • Prieto-Davo, A; Dias, T; Gomes, SE; Rodrigues, S; Parera-Valadezl, Y; Borralho, PM; Pereira, F; Rodrigues, CMP; Santos-Sanches, I; Gaudencio, SP. 2016. The Madeira Archipelago As a Significant Source of Marine-Derived Actinomycete Diversity with Anticancer and Antimicrobial Potential. Frontiers in Microbiology, 7, DOI: 10.3389/fmicb.2016.01594
  • Pereira, F; Latino, DARS; Gaudencio, SP. 2015. QSAR-Assisted Virtual Screening of Lead-Like Molecules from Marine and Microbial Natural Sources for Antitumor and Antibiotic Drug Discovery. MOLECULES, 20, DOI: 10.3390/molecules20034848
  • Gaudencio, SP; Pereira, F. 2015. Dereplication: racing to speed up the natural products discovery process. NATURAL PRODUCT REPORTS, 32, DOI: 10.1039/c4np00134f
  • Marisa Paulino, Florbela Pereira, Tiago Dias, Ilda Santos-Sanches, Susana PGaudêncio. 2014. Phylogenetic and chemical diversity of MAR4 streptomycete lineage. Frontiers in Marine Science, DOI: 10.3389/conf.FMARS.2014.02.00055
  • Sara Rodrigues, Tiago Dias, Florbela Pereira, Ilda Santos-Sanches, Susana PGaudêncio. 2014. Marine actinomycetes from Madeira Archipelago preliminary taxonomic studies. Frontiers in Marine Science, DOI: 10.3389/conf.FMARS.2014.02.00054
  • Pereira, Florbela Latino Diogo ARSGaudêncio Susana Pereira. 2014. A QSAR approach for virtual screening of lead-like molecules en route to antitumor and antibiotic drugs from marine and microbial natural products. Frontiers in Marine Science, DOI: 10.3389/conf.FMARS.2014.02.00062
  • Pereira, F; Latino, DARS; Gaudencio, SP. 2014. A Chemoinformatics Approach to the Discovery of Lead-Like Molecules from Marine and Microbial Sources En Route to Antitumor and Antibiotic Drugs. Marine Drugs, 12, DOI: 10.3390/md12020757

Main research interests

  • Discovery and development of lead-like agents for drug discovery and biotechnological applications. Identification of new bioactive small molecules from marine-derived actinomycete sources collected off the Atlantic.


  • PhD in Organic Chemistry, FCT, NOVA (2006)
  • MSc in Technological Organic Chemistry, FCT, NOVA (2001)
  • Graduation in Chemistry, FCUL (1998)