Paul Knochel, University Munich, Germany
Polyfunctional Heterocyclic Organometallics in Synthesis
Host: Maria Manuel Marques, LAQV - FCT NOVA
Transition metal catalyzed cross-couplings are important tools for the pharmaceutical and agrochemical industries. Herein, we will first describe the most important methods for preparing polyfunctional organozinc and organomagnesium reagents and describe their use for performing cobalt-catalyzed cross-couplings and aminations.
Paul Knochel did his Ph.D at the ETH-Zürich with Prof. D. Seebach. He spent 4 years at the CNRS at the University Pierre and Marie Curie in Paris with Prof. J.-F. Normant, followed by a post-doc at Princeton University with Prof. M. F. Semmelhack. In 1987, he became Assistant Professor at the University of Michigan at Ann Arbor, in 1991, became Full Professor at this University and in 1992, moved to Philipps-University at Marburg as C4-Professor in Organic Chemistry.
In 1999, he moved to the Chemistry Department of Ludwig-Maximilians-University in Munich. His research interests include the development of novel organometallic reagents and methods for use in organic synthesis, asymmetric catalysis and natural product synthesis. Over 900 publications (including 35 books) and 40 patents.